Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction

Satoshi Kurisu, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Kenji Nishioka, Takashi Umemura, Suji Nakamura, Masashi Yoshida, Hikaru Sato

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Abstract

A 74-year-old woman with hypertension and bronchial asthma had chest discomfort at rest and 4 days later was admitted to her nearby hospital because of the sudden onset of right hemiparesis. The hemiparesis had almost disappeared within 24h of onset, but because an electrocardiogram showed sinus tachycardia and diffuse symmetrical T-wave inversion, she was referred for cardiac examination. Coronary angiography did not reveal any significant coronary artery stenosis, but left ventriculography revealed severe hypokinesis of the left ventricular apical region, which contained a 4x4-mm solid thrombus moving freely with a wavy motion. Moreover, the activity of both protein C and protein S had decreased. The thrombus disappeared after 2 weeks of anticoagulant treatment with warfarin. Her clinical course suggested that the transient cerebral ischemic attack was caused by embolism of the left ventricular thrombus associated with 'tako-tsubo-like left ventricular dysfunction'.

Original languageEnglish
Pages (from-to)556-558
Number of pages3
JournalCirculation Journal
Volume67
Issue number6
DOIs
Publication statusPublished - Jun 1 2003

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Keywords

  • Cerebral ischemia
  • Protein C
  • Tako-tsubo
  • Thrombus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Kurisu, S., Inoue, I., Kawagoe, T., Ishihara, M., Shimatani, Y., Nishioka, K., Umemura, T., Nakamura, S., Yoshida, M., & Sato, H. (2003). Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction. Circulation Journal, 67(6), 556-558. https://doi.org/10.1253/circj.67.556