Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction

Satoshi Kurisu, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Kenji Nishioka, Takashi Umemura, Suji Nakamura, Masashi Yoshida, Hikaru Sato

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

A 74-year-old woman with hypertension and bronchial asthma had chest discomfort at rest and 4 days later was admitted to her nearby hospital because of the sudden onset of right hemiparesis. The hemiparesis had almost disappeared within 24h of onset, but because an electrocardiogram showed sinus tachycardia and diffuse symmetrical T-wave inversion, she was referred for cardiac examination. Coronary angiography did not reveal any significant coronary artery stenosis, but left ventriculography revealed severe hypokinesis of the left ventricular apical region, which contained a 4x4-mm solid thrombus moving freely with a wavy motion. Moreover, the activity of both protein C and protein S had decreased. The thrombus disappeared after 2 weeks of anticoagulant treatment with warfarin. Her clinical course suggested that the transient cerebral ischemic attack was caused by embolism of the left ventricular thrombus associated with 'tako-tsubo-like left ventricular dysfunction'.

Original languageEnglish
Pages (from-to)556-558
Number of pages3
JournalCirculation Journal
Volume67
Issue number6
Publication statusPublished - Jun 1 2003
Externally publishedYes

Fingerprint

Left Ventricular Dysfunction
Thrombosis
Paresis
Sinus Tachycardia
Coronary Stenosis
Protein S
Transient Ischemic Attack
Warfarin
Protein C
Embolism
Coronary Angiography
Anticoagulants
Electrocardiography
Thorax
Asthma
Hypertension
Therapeutics

Keywords

  • Cerebral ischemia
  • Protein C
  • Tako-tsubo
  • Thrombus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology

Cite this

Kurisu, S., Inoue, I., Kawagoe, T., Ishihara, M., Shimatani, Y., Nishioka, K., ... Sato, H. (2003). Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction. Circulation Journal, 67(6), 556-558.

Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction. / Kurisu, Satoshi; Inoue, Ichiro; Kawagoe, Takuji; Ishihara, Masaharu; Shimatani, Yuji; Nishioka, Kenji; Umemura, Takashi; Nakamura, Suji; Yoshida, Masashi; Sato, Hikaru.

In: Circulation Journal, Vol. 67, No. 6, 01.06.2003, p. 556-558.

Research output: Contribution to journalArticle

Kurisu, S, Inoue, I, Kawagoe, T, Ishihara, M, Shimatani, Y, Nishioka, K, Umemura, T, Nakamura, S, Yoshida, M & Sato, H 2003, 'Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction', Circulation Journal, vol. 67, no. 6, pp. 556-558.
Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Nishioka K et al. Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction. Circulation Journal. 2003 Jun 1;67(6):556-558.
Kurisu, Satoshi ; Inoue, Ichiro ; Kawagoe, Takuji ; Ishihara, Masaharu ; Shimatani, Yuji ; Nishioka, Kenji ; Umemura, Takashi ; Nakamura, Suji ; Yoshida, Masashi ; Sato, Hikaru. / Left ventricular apical thrombus formation in a patient with suspected tako-tsubo-like left ventricular dysfunction. In: Circulation Journal. 2003 ; Vol. 67, No. 6. pp. 556-558.
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AB - A 74-year-old woman with hypertension and bronchial asthma had chest discomfort at rest and 4 days later was admitted to her nearby hospital because of the sudden onset of right hemiparesis. The hemiparesis had almost disappeared within 24h of onset, but because an electrocardiogram showed sinus tachycardia and diffuse symmetrical T-wave inversion, she was referred for cardiac examination. Coronary angiography did not reveal any significant coronary artery stenosis, but left ventriculography revealed severe hypokinesis of the left ventricular apical region, which contained a 4x4-mm solid thrombus moving freely with a wavy motion. Moreover, the activity of both protein C and protein S had decreased. The thrombus disappeared after 2 weeks of anticoagulant treatment with warfarin. Her clinical course suggested that the transient cerebral ischemic attack was caused by embolism of the left ventricular thrombus associated with 'tako-tsubo-like left ventricular dysfunction'.

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