Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

Hiroyuki Hanakawa; Yorihisa Orita; Yasuharu Sato; Kinya Uno; Kazunori Nishizaki; Tadashi Yoshino

Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

Hiroyuki Hanakawa, Yorihisa Orita, Yasuharu Sato, Kinya Uno, Kazunori Nishizaki, Tadashi Yoshino

Research output: Contribution to journal › Article › peer-review

Abstract

We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

Original language	English
Pages (from-to)	265-269
Number of pages	5
Journal	Acta medica Okayama
Volume	67
Issue number	4
Publication status	Published - 2013

Keywords

Lymphoproliferative disorders
Methotrexate
Oropharynx
Ulceration

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders",

abstract = "We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.",

keywords = "Lymphoproliferative disorders, Methotrexate, Oropharynx, Ulceration",

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T1 - Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

AU - Hanakawa, Hiroyuki

AU - Orita, Yorihisa

AU - Sato, Yasuharu

AU - Uno, Kinya

AU - Nishizaki, Kazunori

AU - Yoshino, Tadashi

PY - 2013

Y1 - 2013

N2 - We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

AB - We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

KW - Lymphoproliferative disorders

KW - Methotrexate

KW - Oropharynx

KW - Ulceration

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JO - Acta Medica Okayama

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IS - 4

ER -

Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

Abstract

Keywords

ASJC Scopus subject areas

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