Large supratentorial ectopic ependymoma with massive calcification and cyst formation - Case report

Shigeki Ono, Tomotsugu Ichikawa, Yasuhiro Ono, Isao Date

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A 6-year-old boy presented with a large supratentorial ependymoma with massive calcification and central cyst formation manifesting as generalized convulsion and right hemiparesis. Computed tomography and magnetic resonance imaging showed a large, poorly enhanced, left frontal mass with massive calcification and a central cyst. Angiography revealed no extracranial blood supply to the tumor, which was supplied by branches of the left middle cerebral artery. The patient underwent total resection of the tumor, which was located in the parenchyma with no dural attachment. The tumor was clearly demarcated and dissected subpially from the surrounding brain parenchyma. The surgical findings suggested no relationship with the lateral ventricular system. Histological examination of the tumor demonstrated perivascular pseudorosette formation and mitosis with massive calcification, and immunocytochemical reactivity for glial fibrillary acidic protein and epithelial membrane antigen, but not synaptophysin. These findings were compatible with ependymoma, World Health Organization grade 2. Postoperative magnetic resonance imaging clearly showed that the tumor was located in the intradural, intraaxial space with no relationship to the ventricles.

Original languageEnglish
Pages (from-to)424-428
Number of pages5
JournalNeurologia Medico-Chirurgica
Volume44
Issue number8
DOIs
Publication statusPublished - Aug 2004

Fingerprint

Ependymoma
Cysts
Neoplasms
Magnetic Resonance Imaging
Mucin-1
Synaptophysin
Glial Fibrillary Acidic Protein
Middle Cerebral Artery
Paresis
Mitosis
Angiography
Seizures
Tomography
Brain

Keywords

  • Calcification
  • Ectopic ependymoma
  • Supratentorial ependymoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Large supratentorial ectopic ependymoma with massive calcification and cyst formation - Case report. / Ono, Shigeki; Ichikawa, Tomotsugu; Ono, Yasuhiro; Date, Isao.

In: Neurologia Medico-Chirurgica, Vol. 44, No. 8, 08.2004, p. 424-428.

Research output: Contribution to journalArticle

Ono, Shigeki ; Ichikawa, Tomotsugu ; Ono, Yasuhiro ; Date, Isao. / Large supratentorial ectopic ependymoma with massive calcification and cyst formation - Case report. In: Neurologia Medico-Chirurgica. 2004 ; Vol. 44, No. 8. pp. 424-428.
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