Laminar cortical necrosis in central nervous system lupus: sequential changes in MR images

K. Kashihara, S. Fukase, I. Kohira, K. Abe

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A 44-year-old woman with systemic lupus erythematosus developed central nervous system lupus presenting with headache, fever, cloudiness of consciousness, and psychotic symptoms. T1-weighted and proton MR images showed laminar high intensity lesions in the parietal and temporal cortex bilaterally. T2-weighted images of the lesions showed low signal intensity. Treatment with corticosteroids alleviated the clinical symptoms within 7 months. The low T2 and high T1 signal abnormalities disappeared in a year and in 5 years, respectively. The laminar cortical lesions on MR images were suggested to represent cortical necrosis associated with central nervous system lupus. Copyright (C) 1999 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)145-147
Number of pages3
JournalClinical Neurology and Neurosurgery
Issue number2
Publication statusPublished - Jun 1 1999



  • Central nervous system
  • Laminar necrosis
  • Magnetic resonance imaging
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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