TY - JOUR
T1 - Laboratory versus nature
T2 - The two sides of the Drosophila circadian clock
AU - Menegazzi, Pamela
AU - Yoshii, Taishi
AU - Helfrich-Förster, Charlotte
N1 - Funding Information:
We thank C.P. Kyriacou and R. Costa and 2 unknown reviewers for comments on the manuscript, Stefano Vanin for help with the experiments in Treviso, Dirk Rieger for help in Würzburg, Atefeh Pooryasin for help with the Noldus software, and Jochen Krauss and Ingolf Steffan-Dewenter for letting us use their climate chamber for simulating the natural-like temperature and light cycles. C.H.-F. acknowledges financial support from the European Community (the 6th Framework Project EUCLOCK no. 018741) and the DFG (Fo207/12-3; 13-1). T.Y. acknowledges the JSPS for a Grant-in-Aid for Research Activity Start-up.
Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/12
Y1 - 2012/12
N2 - The daily pattern of animal behavior is thought to be of potential enormous importance for survival. Here, we compared the daily activity pattern of Drosophila melanogaster wild-type flies and the clock-impaired mutants, per01 and ClkJrk, under pseudo-natural conditions and laboratory conditions with natural-like temperature profiles. We found that clock-impaired flies respond stronger to changes in the environment, namely temperature increases, than wild-type flies. We hypothesize that the circadian clock may suppress unproductive activity in response to temperature fluctuations but that such suppression can be overcome in extreme conditions that are likely life-threatening for the flies. Thus, possessing a clock seems to be of adaptive significance.
AB - The daily pattern of animal behavior is thought to be of potential enormous importance for survival. Here, we compared the daily activity pattern of Drosophila melanogaster wild-type flies and the clock-impaired mutants, per01 and ClkJrk, under pseudo-natural conditions and laboratory conditions with natural-like temperature profiles. We found that clock-impaired flies respond stronger to changes in the environment, namely temperature increases, than wild-type flies. We hypothesize that the circadian clock may suppress unproductive activity in response to temperature fluctuations but that such suppression can be overcome in extreme conditions that are likely life-threatening for the flies. Thus, possessing a clock seems to be of adaptive significance.
KW - ClkJrk
KW - Drosophila melanogaster
KW - afternoon peak
KW - clock mutants
KW - locomotor activity pattern
KW - per01
KW - pseudo-natural conditions
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U2 - 10.1177/0748730412463181
DO - 10.1177/0748730412463181
M3 - Article
C2 - 23223369
AN - SCOPUS:84870806928
VL - 27
SP - 433
EP - 442
JO - Journal of Biological Rhythms
JF - Journal of Biological Rhythms
SN - 0748-7304
IS - 6
ER -