Isolation and Characterization of Two Novel Nematicidal Depsipeptides from an Imperfect Fungus, Strain D1084

Kazuyoshi Kawazu, Tadashi Murakami, Youko Ono, Hiroshi Kanzaki, Akio Kobayashi, Takashi Mikawa, Nobuji Yoshikawa

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23 Citations (Scopus)

Abstract

Two novel nematicidal cyclodepsipeptides, designated bursaphelocides A and B, were isolated from the culture filtrate of an imperfect fungus, strain D1084, belonging to Mycelia sterilia. Bursaphelocide A (1), containing 2-hydroxy-3-methylpentanoic acid, proline, isoleucine, N-methylalanine, N-methylvaline, and β-alanine in sequence, and bursaphelocide B (2), comprising 4-methylproline instead of proline in 1, are novel 2-hydroxy-3-methylpentanoic acid analogues of insecticidal destruxins.

Original languageEnglish
Pages (from-to)98-101
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume57
Issue number1
DOIs
Publication statusPublished - Jan 1 1993

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ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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