Isolation and Characterization of Two Novel Nematicidal Depsipeptides from an Imperfect Fungus, Strain D1084

Kazuyoshi Kawazu; Tadashi Murakami; Youko Ono; Hiroshi Kanzaki; Akio Kobayashi; Takashi Mikawa; Nobuji Yoshikawa

doi:10.1271/bbb.57.98

Isolation and Characterization of Two Novel Nematicidal Depsipeptides from an Imperfect Fungus, Strain D1084

Kazuyoshi Kawazu, Tadashi Murakami, Youko Ono, Hiroshi Kanzaki, Akio Kobayashi, Takashi Mikawa, Nobuji Yoshikawa

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Two novel nematicidal cyclodepsipeptides, designated bursaphelocides A and B, were isolated from the culture filtrate of an imperfect fungus, strain D1084, belonging to Mycelia sterilia. Bursaphelocide A (1), containing 2-hydroxy-3-methylpentanoic acid, proline, isoleucine, N-methylalanine, N-methylvaline, and β-alanine in sequence, and bursaphelocide B (2), comprising 4-methylproline instead of proline in 1, are novel 2-hydroxy-3-methylpentanoic acid analogues of insecticidal destruxins.

Original language	English
Pages (from-to)	98-101
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	57
Issue number	1
DOIs	https://doi.org/10.1271/bbb.57.98
Publication status	Published - 1993

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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abstract = "Two novel nematicidal cyclodepsipeptides, designated bursaphelocides A and B, were isolated from the culture filtrate of an imperfect fungus, strain D1084, belonging to Mycelia sterilia. Bursaphelocide A (1), containing 2-hydroxy-3-methylpentanoic acid, proline, isoleucine, N-methylalanine, N-methylvaline, and β-alanine in sequence, and bursaphelocide B (2), comprising 4-methylproline instead of proline in 1, are novel 2-hydroxy-3-methylpentanoic acid analogues of insecticidal destruxins.",

author = "Kazuyoshi Kawazu and Tadashi Murakami and Youko Ono and Hiroshi Kanzaki and Akio Kobayashi and Takashi Mikawa and Nobuji Yoshikawa",

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T1 - Isolation and Characterization of Two Novel Nematicidal Depsipeptides from an Imperfect Fungus, Strain D1084

AU - Kawazu, Kazuyoshi

AU - Murakami, Tadashi

AU - Ono, Youko

AU - Kanzaki, Hiroshi

AU - Kobayashi, Akio

AU - Mikawa, Takashi

AU - Yoshikawa, Nobuji

PY - 1993

Y1 - 1993

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AB - Two novel nematicidal cyclodepsipeptides, designated bursaphelocides A and B, were isolated from the culture filtrate of an imperfect fungus, strain D1084, belonging to Mycelia sterilia. Bursaphelocide A (1), containing 2-hydroxy-3-methylpentanoic acid, proline, isoleucine, N-methylalanine, N-methylvaline, and β-alanine in sequence, and bursaphelocide B (2), comprising 4-methylproline instead of proline in 1, are novel 2-hydroxy-3-methylpentanoic acid analogues of insecticidal destruxins.

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Isolation and Characterization of Two Novel Nematicidal Depsipeptides from an Imperfect Fungus, Strain D1084

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