Isolation and characterization of the plant immune-priming compounds Imprimatin B3 and -B4, potentiators of disease resistance in Arabidopsis thaliana.

Yoshiteru Noutoshi, Masateru Okazaki, Ken Shirasu

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Plant activators are chemical crop protectants that fortify the immune system in plants. Unlike pesticides that target pathogens, plant activators provide durable effects against a broad spectrum of diseases, which have not been overcome by pathogenic microbes. Plant activators are not only useful agrochemicals, but can also help to elucidate the details of the plant immune system. Using an established high-throughput screening procedure, we previously identified 5 compounds, designated as Imprimatins, which prime plant immune response. These compounds increased disease resistance against pathogenic Pseudomonas bacteria in Arabidopsis plants by inhibiting 2 salicylic acid (SA) glucosyltransferases (SAGTs), resulting in accumulation of the phytohormone SA. Here, we report the isolation of 2 additional Imprimatins, B3 and B4, which are structurally similar to Imprimatin B1 and B2. Because these compounds did not have strong inhibitory effects on SAGTs in vitro, they may exert their function after metabolic conversion in vivo.

Original languageEnglish
Pages (from-to)1526-1528
Number of pages3
JournalPlant Signaling and Behavior
Volume7
Issue number12
DOIs
Publication statusPublished - Dec 2012

Fingerprint

disease resistance
Arabidopsis thaliana
glucosyltransferases
salicylic acid
immune system
agrochemicals
plant pathogens
plant hormones
Pseudomonas
pesticides
Arabidopsis
immune response
screening
microorganisms
bacteria
crops

Keywords

  • Chemical biology
  • Disease resistance
  • Plant activator
  • Plant immunity
  • Salicylic acid

ASJC Scopus subject areas

  • Plant Science

Cite this

Isolation and characterization of the plant immune-priming compounds Imprimatin B3 and -B4, potentiators of disease resistance in Arabidopsis thaliana. / Noutoshi, Yoshiteru; Okazaki, Masateru; Shirasu, Ken.

In: Plant Signaling and Behavior, Vol. 7, No. 12, 12.2012, p. 1526-1528.

Research output: Contribution to journalArticle

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