Isolation and characterization of the mouse corticotropin-β-lipotropin precursor gene and a related pseudogene

Mitsue Notake, Takamasa Tobimatsu, Yumiko Watanabe, Hideo Takahashi, Masayoshi Mishina, Shosaku Numa

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Two mouse genomic DNA sequences homologous with human corticotropin-β-lipotropin precursor gene sequences have been cloned. One of them represents the functional corticotropin-β-lipotropin precursor gene, which exhibits a structural organization similar to those of its bovine and human counterparts. The other represents a pseudogene that corresponds to the functional mouse gene sequence encoding the carboxy-terminal 143 amino acid residues (including corticotropin and β-lipotropin) and the 3′-untranslated region.

Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalFEBS Letters
Volume156
Issue number1
DOIs
Publication statusPublished - May 30 1983
Externally publishedYes

Fingerprint

beta-Lipotropin
Pseudogenes
Adrenocorticotropic Hormone
Genes
DNA sequences
3' Untranslated Regions
Amino Acids

Keywords

  • Direct repeat
  • DNA sequence
  • Exon/intron
  • Mouse corticotropin-β-lipotropin precursor gene
  • Pseudogene
  • Recombinant DNA

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Isolation and characterization of the mouse corticotropin-β-lipotropin precursor gene and a related pseudogene. / Notake, Mitsue; Tobimatsu, Takamasa; Watanabe, Yumiko; Takahashi, Hideo; Mishina, Masayoshi; Numa, Shosaku.

In: FEBS Letters, Vol. 156, No. 1, 30.05.1983, p. 67-71.

Research output: Contribution to journalArticle

Notake, Mitsue ; Tobimatsu, Takamasa ; Watanabe, Yumiko ; Takahashi, Hideo ; Mishina, Masayoshi ; Numa, Shosaku. / Isolation and characterization of the mouse corticotropin-β-lipotropin precursor gene and a related pseudogene. In: FEBS Letters. 1983 ; Vol. 156, No. 1. pp. 67-71.
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