TY - JOUR
T1 - Isolated metastasis of lung cancer to the thyroid gland
AU - Osawa, Masahiro
AU - Takigawa, Nagio
AU - Kiura, Katsuyuki
AU - Ichimura, Kouichi
AU - Matsuoka, Junji
AU - Hotta, Katsuyuki
AU - Tabata, Masahiro
AU - Tanimoto, Mitsune
PY - 2007/10
Y1 - 2007/10
N2 - A 67-year-old man with lung cancer developed an isolated metastasis to the thyroid gland. The patient had undergone a right upper lobectomy, followed by chemotherapy consisting of cisplatin and etoposide based on post-surgical diagnosis of small cell lung cancer. Four years later, he had an isolated metastasis to the thyroid gland. The patient underwent a metastasectomy and adjuvant chemotherapy including cisplatin and irinotecan. The cancer cells in resected thyroid tumor had large nuclei and cytoplasm, and expressed the neuroendocrine markers, CD56 and chromogranin A. Retrospectively, the primary lung cancer consisted of both small cell and large cell cancer, and the latter was consistent with the pathological finding of the thyroid tumor. This is the first report to document an isolated recurrence of the lung cancer to the thyroid.
AB - A 67-year-old man with lung cancer developed an isolated metastasis to the thyroid gland. The patient had undergone a right upper lobectomy, followed by chemotherapy consisting of cisplatin and etoposide based on post-surgical diagnosis of small cell lung cancer. Four years later, he had an isolated metastasis to the thyroid gland. The patient underwent a metastasectomy and adjuvant chemotherapy including cisplatin and irinotecan. The cancer cells in resected thyroid tumor had large nuclei and cytoplasm, and expressed the neuroendocrine markers, CD56 and chromogranin A. Retrospectively, the primary lung cancer consisted of both small cell and large cell cancer, and the latter was consistent with the pathological finding of the thyroid tumor. This is the first report to document an isolated recurrence of the lung cancer to the thyroid.
KW - Adjuvant chemotherapy
KW - Large cell carcinoma
KW - Lung cancer
KW - Metastasectomy
KW - Recurrence
KW - Small cell carcinoma
KW - Thyroid
UR - http://www.scopus.com/inward/record.url?scp=34548509966&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548509966&partnerID=8YFLogxK
U2 - 10.1016/j.lungcan.2007.04.014
DO - 10.1016/j.lungcan.2007.04.014
M3 - Article
C2 - 17553590
AN - SCOPUS:34548509966
SN - 0169-5002
VL - 58
SP - 156
EP - 158
JO - Lung Cancer
JF - Lung Cancer
IS - 1
ER -
