Iron-catalyzed C(sp2)-H bond functionalization with organoboron compounds

Rui Shang, Laurean Ilies, Sobi Asako, Eiichi Nakamura

Research output: Contribution to journalArticle

110 Citations (Scopus)

Abstract

We report here that an iron-catalyzed directed C-H functionalization reaction allows the coupling of a variety of aromatic, heteroaromatic, and olefinic substrates with alkenyl and aryl boron compounds under mild oxidative conditions. We rationalize these results by the involvement of an organoiron(III) reactive intermediate that is responsible for the C-H bond-activation process. A zinc salt is crucial to promote the transfer of the organic group from the boron atom to the iron(III) atom.

Original languageEnglish
Pages (from-to)14349-14352
Number of pages4
JournalJournal of the American Chemical Society
Volume136
Issue number41
DOIs
Publication statusPublished - Oct 15 2014

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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