Abstract
We report here that an iron-catalyzed directed C-H functionalization reaction allows the coupling of a variety of aromatic, heteroaromatic, and olefinic substrates with alkenyl and aryl boron compounds under mild oxidative conditions. We rationalize these results by the involvement of an organoiron(III) reactive intermediate that is responsible for the C-H bond-activation process. A zinc salt is crucial to promote the transfer of the organic group from the boron atom to the iron(III) atom.
| Original language | English |
|---|---|
| Pages (from-to) | 14349-14352 |
| Number of pages | 4 |
| Journal | Journal of the American Chemical Society |
| Volume | 136 |
| Issue number | 41 |
| DOIs | |
| Publication status | Published - Oct 15 2014 |
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry
Fingerprint Dive into the research topics of 'Iron-catalyzed C(sp<sup>2</sup>)-H bond functionalization with organoboron compounds'. Together they form a unique fingerprint.
Cite this
Shang, R., Ilies, L., Asako, S., & Nakamura, E. (2014). Iron-catalyzed C(sp2)-H bond functionalization with organoboron compounds. Journal of the American Chemical Society, 136(41), 14349-14352. https://doi.org/10.1021/ja5070763