Iridium-catalyzed dehydrogenative silylation of azulenes based on regioselective C-H bond activation

Masahito Murai, Keishi Takami, Hirotaka Takeshima, Kazuhiko Takai

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Use of an iridium catalyst allowed the efficient dehydrogenative functionalization of C-H bonds of azulenes with the production of hydrogen as the sole byproduct. The reaction occurred with excellent chemo- and regioselectivities to provide 2-silylazulenes even without any directing groups. Effective conjugation through the 2-position of the azulene ring was demonstrated by the unique stimuli-responsiveness against an acid-base reaction.

Original languageEnglish
Pages (from-to)1798-1801
Number of pages4
JournalOrganic Letters
Volume17
Issue number7
DOIs
Publication statusPublished - Apr 3 2015

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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