Ionic amino acids: Application as organocatalysts in the aza-Michael reaction

Naoki Morimoto; Yasuo Takeuchi; Yuta Nishina

doi:10.1016/j.molcata.2012.11.012

Ionic amino acids: Application as organocatalysts in the aza-Michael reaction

Naoki Morimoto, Yasuo Takeuchi, Yuta Nishina

Research output: Contribution to journal › Article

10 Citations (Scopus)

Abstract

The ethyl methyl imidazolium salts of amino acids, [emim][AA], have been used as catalysts in the aza-Michael reaction. Furthermore, when chiral amino acids were used, a stereoselective reaction was achieved. The mechanism of the transformation was verified by the detection of a key intermediate by electrospray ionization mass spectroscopy (ESI-MS).

Original language	English
Pages (from-to)	31-37
Number of pages	7
Journal	Journal of Molecular Catalysis A: Chemical
Volume	368-369
DOIs	https://doi.org/10.1016/j.molcata.2012.11.012
Publication status	Published - Mar 2013

Keywords

Amino acid
Asymmetric reaction
ESI-MS
Organocatalyst
aza-Michael reaction

ASJC Scopus subject areas

Catalysis
Process Chemistry and Technology
Physical and Theoretical Chemistry

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10.1016/j.molcata.2012.11.012

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Morimoto, N., Takeuchi, Y., & Nishina, Y. (2013). Ionic amino acids: Application as organocatalysts in the aza-Michael reaction. Journal of Molecular Catalysis A: Chemical, 368-369, 31-37. https://doi.org/10.1016/j.molcata.2012.11.012

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abstract = "The ethyl methyl imidazolium salts of amino acids, [emim][AA], have been used as catalysts in the aza-Michael reaction. Furthermore, when chiral amino acids were used, a stereoselective reaction was achieved. The mechanism of the transformation was verified by the detection of a key intermediate by electrospray ionization mass spectroscopy (ESI-MS).",

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