In vitro growth experiments were conducted to evaluate the ability of vulnibactin, a siderophore produced by Vibrio vulnificus, to sequester transferrin- or lactoferrin-bound iron for growth. Comparative studies with the strain producing vulnibactin and its exocellular protease-deficient mutant revealed the involvement of the protease in addition to vulnibactin in effective utilization of iron ion (Fe3+) bound to transferrin and lactoferrin. It appears that the protease causes cleavage of these proteins, thereby making bound iron more accessible to vulnibactin.
|Number of pages||4|
|Journal||MICROBIOLOGY and IMMUNOLOGY|
|Publication status||Published - 1996|
- Exocellular protease
- Iron assimilation
- Vibrio vulnificus
ASJC Scopus subject areas