Involvement of the Vibrio parahaemolyticus pvsC gene in export of the siderophore vibrioferrin

Tomotaka Tanabe, Hiroshi Nakao, Teruo Kuroda, Tomofusa Tsuchiya, Shigeo Yamamoto

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The pvsC gene of unknown function has been found in the iron-regulated vibrioferrin biosynthesis operon of Vibrio parahaemolyticus (Tanabe, T. et al., J. Bacteriol. 185: 6938-6949, 2003). The amino acid sequence deduced from the gene showed significant similarity to 12-transmembrane segment efflux pumps belonging to the major facilitator superfamily. A nonpolar deletion of pvsC in V. parahaemolyticus resulted in a reduced release of vibrioferrin into the medium. Vibrioferrin release could be regained by introducing the intact pvsC gene on a complementing plasmid. These results indicate that the pvsC gene product functions as an inner membrane exporter of vibrioferrin.

Original languageEnglish
Pages (from-to)871-876
Number of pages6
JournalMicrobiology and Immunology
Volume50
Issue number11
Publication statusPublished - 2006

Fingerprint

Vibrio parahaemolyticus
Siderophores
Genes
Operon
Amino Acid Sequence
Plasmids
Iron
Membranes
vibrioferrin

Keywords

  • pvsC
  • Siderophore exporter
  • Vibrio parahaemolyticus
  • Vibrioferrin

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Microbiology

Cite this

Tanabe, T., Nakao, H., Kuroda, T., Tsuchiya, T., & Yamamoto, S. (2006). Involvement of the Vibrio parahaemolyticus pvsC gene in export of the siderophore vibrioferrin. Microbiology and Immunology, 50(11), 871-876.

Involvement of the Vibrio parahaemolyticus pvsC gene in export of the siderophore vibrioferrin. / Tanabe, Tomotaka; Nakao, Hiroshi; Kuroda, Teruo; Tsuchiya, Tomofusa; Yamamoto, Shigeo.

In: Microbiology and Immunology, Vol. 50, No. 11, 2006, p. 871-876.

Research output: Contribution to journalArticle

Tanabe, T, Nakao, H, Kuroda, T, Tsuchiya, T & Yamamoto, S 2006, 'Involvement of the Vibrio parahaemolyticus pvsC gene in export of the siderophore vibrioferrin', Microbiology and Immunology, vol. 50, no. 11, pp. 871-876.
Tanabe, Tomotaka ; Nakao, Hiroshi ; Kuroda, Teruo ; Tsuchiya, Tomofusa ; Yamamoto, Shigeo. / Involvement of the Vibrio parahaemolyticus pvsC gene in export of the siderophore vibrioferrin. In: Microbiology and Immunology. 2006 ; Vol. 50, No. 11. pp. 871-876.
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