Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture

Hiromi Yamamoto, Toru Kawada, Atsunori Kamiya, Shunichi Miyazaki, Masaru Sugimachi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The modalities of acupuncture can be broadly classified into manual acupuncture (MA) and electroacupuncture (EA). Although MA has been reported to cause winding of tissue around the needle and subsequent activation of the sensory mechanoreceptors and nociceptors, the sensory mechanisms of acupuncture stimulation are not fully understood. To test the hypothesis that the involvement of the mechanoreceptors in the sensory mechanism is different in MA and EA, we examined the effects of a stretch-activated channel blocker gadolinium on the hemodynamic responses to hind limb MA and EA in anesthetized rats (n. =9). Gadolinium significantly attenuated the MA-induced bradycardic response (-22 ± 5 vs. -10 ± 3 bpm, P < 0.05) and tended to attenuate the MA-induced depressor response (-30 ±5 vs. -18 ±4 mm Hg, P=0.06). On the other hand, gadolinium significantly attenuated both the EA-induced bradycardic (-22 ±5 vs. -9 ±4. bpm, P < 0.01) and depressor responses (-32 ±6 vs. -15 ±5. mm. Hg, P < 0.01). These results indicate that the mechanoreceptors are involved in the sensory mechanisms for both MA and EA.

Original languageEnglish
Pages (from-to)27-31
Number of pages5
JournalAutonomic Neuroscience: Basic and Clinical
Volume160
Issue number1-2
DOIs
Publication statusPublished - Feb 24 2011
Externally publishedYes

Fingerprint

Mechanoreceptors
Acupuncture
Electroacupuncture
Gadolinium
Nociceptors
Needles
Extremities
Hemodynamics

Keywords

  • Acupuncture
  • Aortic depressor nerve
  • Arterial blood pressure
  • Gadolinium
  • Heart rate
  • Mechanoreceptor

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture. / Yamamoto, Hiromi; Kawada, Toru; Kamiya, Atsunori; Miyazaki, Shunichi; Sugimachi, Masaru.

In: Autonomic Neuroscience: Basic and Clinical, Vol. 160, No. 1-2, 24.02.2011, p. 27-31.

Research output: Contribution to journalArticle

Yamamoto, Hiromi ; Kawada, Toru ; Kamiya, Atsunori ; Miyazaki, Shunichi ; Sugimachi, Masaru. / Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture. In: Autonomic Neuroscience: Basic and Clinical. 2011 ; Vol. 160, No. 1-2. pp. 27-31.
@article{ca5baa6ac3864476b92b53968e2f5973,
title = "Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture",
abstract = "The modalities of acupuncture can be broadly classified into manual acupuncture (MA) and electroacupuncture (EA). Although MA has been reported to cause winding of tissue around the needle and subsequent activation of the sensory mechanoreceptors and nociceptors, the sensory mechanisms of acupuncture stimulation are not fully understood. To test the hypothesis that the involvement of the mechanoreceptors in the sensory mechanism is different in MA and EA, we examined the effects of a stretch-activated channel blocker gadolinium on the hemodynamic responses to hind limb MA and EA in anesthetized rats (n. =9). Gadolinium significantly attenuated the MA-induced bradycardic response (-22 ± 5 vs. -10 ± 3 bpm, P < 0.05) and tended to attenuate the MA-induced depressor response (-30 ±5 vs. -18 ±4 mm Hg, P=0.06). On the other hand, gadolinium significantly attenuated both the EA-induced bradycardic (-22 ±5 vs. -9 ±4. bpm, P < 0.01) and depressor responses (-32 ±6 vs. -15 ±5. mm. Hg, P < 0.01). These results indicate that the mechanoreceptors are involved in the sensory mechanisms for both MA and EA.",
keywords = "Acupuncture, Aortic depressor nerve, Arterial blood pressure, Gadolinium, Heart rate, Mechanoreceptor",
author = "Hiromi Yamamoto and Toru Kawada and Atsunori Kamiya and Shunichi Miyazaki and Masaru Sugimachi",
year = "2011",
month = "2",
day = "24",
doi = "10.1016/j.autneu.2010.11.004",
language = "English",
volume = "160",
pages = "27--31",
journal = "Autonomic Neuroscience: Basic and Clinical",
issn = "1566-0702",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture

AU - Yamamoto, Hiromi

AU - Kawada, Toru

AU - Kamiya, Atsunori

AU - Miyazaki, Shunichi

AU - Sugimachi, Masaru

PY - 2011/2/24

Y1 - 2011/2/24

N2 - The modalities of acupuncture can be broadly classified into manual acupuncture (MA) and electroacupuncture (EA). Although MA has been reported to cause winding of tissue around the needle and subsequent activation of the sensory mechanoreceptors and nociceptors, the sensory mechanisms of acupuncture stimulation are not fully understood. To test the hypothesis that the involvement of the mechanoreceptors in the sensory mechanism is different in MA and EA, we examined the effects of a stretch-activated channel blocker gadolinium on the hemodynamic responses to hind limb MA and EA in anesthetized rats (n. =9). Gadolinium significantly attenuated the MA-induced bradycardic response (-22 ± 5 vs. -10 ± 3 bpm, P < 0.05) and tended to attenuate the MA-induced depressor response (-30 ±5 vs. -18 ±4 mm Hg, P=0.06). On the other hand, gadolinium significantly attenuated both the EA-induced bradycardic (-22 ±5 vs. -9 ±4. bpm, P < 0.01) and depressor responses (-32 ±6 vs. -15 ±5. mm. Hg, P < 0.01). These results indicate that the mechanoreceptors are involved in the sensory mechanisms for both MA and EA.

AB - The modalities of acupuncture can be broadly classified into manual acupuncture (MA) and electroacupuncture (EA). Although MA has been reported to cause winding of tissue around the needle and subsequent activation of the sensory mechanoreceptors and nociceptors, the sensory mechanisms of acupuncture stimulation are not fully understood. To test the hypothesis that the involvement of the mechanoreceptors in the sensory mechanism is different in MA and EA, we examined the effects of a stretch-activated channel blocker gadolinium on the hemodynamic responses to hind limb MA and EA in anesthetized rats (n. =9). Gadolinium significantly attenuated the MA-induced bradycardic response (-22 ± 5 vs. -10 ± 3 bpm, P < 0.05) and tended to attenuate the MA-induced depressor response (-30 ±5 vs. -18 ±4 mm Hg, P=0.06). On the other hand, gadolinium significantly attenuated both the EA-induced bradycardic (-22 ±5 vs. -9 ±4. bpm, P < 0.01) and depressor responses (-32 ±6 vs. -15 ±5. mm. Hg, P < 0.01). These results indicate that the mechanoreceptors are involved in the sensory mechanisms for both MA and EA.

KW - Acupuncture

KW - Aortic depressor nerve

KW - Arterial blood pressure

KW - Gadolinium

KW - Heart rate

KW - Mechanoreceptor

UR - http://www.scopus.com/inward/record.url?scp=79551539842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79551539842&partnerID=8YFLogxK

U2 - 10.1016/j.autneu.2010.11.004

DO - 10.1016/j.autneu.2010.11.004

M3 - Article

C2 - 21167796

AN - SCOPUS:79551539842

VL - 160

SP - 27

EP - 31

JO - Autonomic Neuroscience: Basic and Clinical

JF - Autonomic Neuroscience: Basic and Clinical

SN - 1566-0702

IS - 1-2

ER -