Invasive non-typeable Haemophilus influenzae infection due to endometritis associated with adenomyosis

Research output: Contribution to journalArticle

Abstract

Background: The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). However, the occurrence of invasive NTHi infection based on gynecologic diseases is still rare. Case presentation: A 51-year-old Japanese woman with a history of adenomyoma presented with fever. Blood cultures and a vaginal discharge culture were positive with NTHi. With the high uptake in the uterus with 67Ga scintigraphy, she was diagnosed with invasive NTHi infection. In addition to antibiotic administrations, a total hysterectomy was performed. The pathological analysis found microabscess formations in adenomyosis. Conclusions: Although NTHi bacteremia consequent to a microabscess in adenomyosis is rare, this case emphasizes the need to consider the uterus as a potential source of infection in patients with underlying gynecological diseases, including an invasive NTHi infection with no known primary focus.

Original languageEnglish
Article number521
JournalBMC Infectious Diseases
Volume20
Issue number1
DOIs
Publication statusPublished - Jul 16 2020

Keywords

  • Adenomyosis
  • Bacteremia
  • Case report
  • Non-typable Haemophilus influenzae
  • β-Lactamase-nonproducing ampicillin-resistance

ASJC Scopus subject areas

  • Infectious Diseases

Fingerprint Dive into the research topics of 'Invasive non-typeable Haemophilus influenzae infection due to endometritis associated with adenomyosis'. Together they form a unique fingerprint.

  • Cite this