Interim report of the Japanese original donor evaluation and management system

The medical consultant system

Tomoyuki Nakagiri, Masayoshi Inoue, Masato Minami, Yasushi Hoshikawa, Masayuki Chida, Toru Bando, Takahiro Oto, Takeshi Shiraishi, Naoya Yamasaki, Juntaro Ashikari, Yoshiki Sawa, Meinoshin Okumura

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: Lung transplantation (LTx) is an established therapy for end-stage lung failure. However, in Japan, the donor organ shortage is extremely severe compared with other developed countries, because of the strict Japanese Organ Transplantation Law. To maximize LTx opportunities in Japan, we have established a special donor evaluation and management system termed the medical consultant (MC) system. Methods: Data from 171 lung donor candidates registered in Japan from May 1998 to May 2012 were obtained and investigated in a retrospective manner. The candidates were separated into the non-MC-intervened and MC-intervened groups, and then data regarding the PaO2/FiO 2 ratio, donation rate and organ survival rate were analyzed and compared between the groups. Results: The PaO2/FiO2 ratio of the MC-intervened group was ameliorated from the time of first brain death diagnosis to organ harvest. Although the base condition of the MC-intervened group was significantly worse than that of the non-MC-intervened group, the donation rates showed no significant difference (0.64 and 0.66, respectively; p = 0.89). There was a difference in the organ survival rate between the non-MC and MC-intervened groups (5-year survival rates of 67.2 and 88.3 %, respectively; p = 0.16). Conclusion: The MC system used for organ donor evaluation and management in Japan has achieved acceptable interim results.

Original languageEnglish
Pages (from-to)1227-1231
Number of pages5
JournalSurgery Today
Volume44
Issue number7
DOIs
Publication statusPublished - 2014

Fingerprint

Consultants
Tissue Donors
Japan
Tissue Survival
Survival Rate
Lung
Brain Death
Lung Transplantation
Organ Transplantation
Developed Countries

Keywords

  • Donation rate
  • Japan Organ Transplantation Network
  • Lung transplantation
  • Medical consultant

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

Nakagiri, T., Inoue, M., Minami, M., Hoshikawa, Y., Chida, M., Bando, T., ... Okumura, M. (2014). Interim report of the Japanese original donor evaluation and management system: The medical consultant system. Surgery Today, 44(7), 1227-1231. https://doi.org/10.1007/s00595-013-0731-1

Interim report of the Japanese original donor evaluation and management system : The medical consultant system. / Nakagiri, Tomoyuki; Inoue, Masayoshi; Minami, Masato; Hoshikawa, Yasushi; Chida, Masayuki; Bando, Toru; Oto, Takahiro; Shiraishi, Takeshi; Yamasaki, Naoya; Ashikari, Juntaro; Sawa, Yoshiki; Okumura, Meinoshin.

In: Surgery Today, Vol. 44, No. 7, 2014, p. 1227-1231.

Research output: Contribution to journalArticle

Nakagiri, T, Inoue, M, Minami, M, Hoshikawa, Y, Chida, M, Bando, T, Oto, T, Shiraishi, T, Yamasaki, N, Ashikari, J, Sawa, Y & Okumura, M 2014, 'Interim report of the Japanese original donor evaluation and management system: The medical consultant system', Surgery Today, vol. 44, no. 7, pp. 1227-1231. https://doi.org/10.1007/s00595-013-0731-1
Nakagiri, Tomoyuki ; Inoue, Masayoshi ; Minami, Masato ; Hoshikawa, Yasushi ; Chida, Masayuki ; Bando, Toru ; Oto, Takahiro ; Shiraishi, Takeshi ; Yamasaki, Naoya ; Ashikari, Juntaro ; Sawa, Yoshiki ; Okumura, Meinoshin. / Interim report of the Japanese original donor evaluation and management system : The medical consultant system. In: Surgery Today. 2014 ; Vol. 44, No. 7. pp. 1227-1231.
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AU - Minami, Masato

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AU - Chida, Masayuki

AU - Bando, Toru

AU - Oto, Takahiro

AU - Shiraishi, Takeshi

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AU - Ashikari, Juntaro

AU - Sawa, Yoshiki

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AB - Purpose: Lung transplantation (LTx) is an established therapy for end-stage lung failure. However, in Japan, the donor organ shortage is extremely severe compared with other developed countries, because of the strict Japanese Organ Transplantation Law. To maximize LTx opportunities in Japan, we have established a special donor evaluation and management system termed the medical consultant (MC) system. Methods: Data from 171 lung donor candidates registered in Japan from May 1998 to May 2012 were obtained and investigated in a retrospective manner. The candidates were separated into the non-MC-intervened and MC-intervened groups, and then data regarding the PaO2/FiO 2 ratio, donation rate and organ survival rate were analyzed and compared between the groups. Results: The PaO2/FiO2 ratio of the MC-intervened group was ameliorated from the time of first brain death diagnosis to organ harvest. Although the base condition of the MC-intervened group was significantly worse than that of the non-MC-intervened group, the donation rates showed no significant difference (0.64 and 0.66, respectively; p = 0.89). There was a difference in the organ survival rate between the non-MC and MC-intervened groups (5-year survival rates of 67.2 and 88.3 %, respectively; p = 0.16). Conclusion: The MC system used for organ donor evaluation and management in Japan has achieved acceptable interim results.

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