Interactions between chromosomal omnipotent suppressors and extrachromosomal effectors in Saccharomyces cerevisiae

Bun ichiro Ono, Yury O. Chernoff, Yumiko Ishino-Arao, Noriko Yamagishi, Sumio Shinoda, Sergey G. Inge-Vechtomov

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9 Citations (Scopus)

Abstract

Chromosomal omnipotent suppressor mutations recovered in ψ+ strains of Saccharomyces cerevisiae were brought into ψ- cytoplasm. SUP46, SUP138 and SUP139 acted as dominant omnipotent suppressors in the ψ- cytoplasm though their suppressor activity was substantially reduced. SUP46 and SUP138 conferred recessive thermosensitivity and antibiotic sensitivity in ψ- cytoplasm as in ψ+ cytoplasm. On the other hand, sup111 through sup115, which acted as recessive omnipotent suppressors in the ψ+ cytoplasm, manifested no, or very low, suppressor activity in the ψ- cytoplasm. They, however, still enhanced the efficiency of the SUP29 tRNA suppressor in ψ- cytoplasm. A multicopy plasmid carrying the wild-type SUP35 gene enhanced the efficiency of sup111 in ψ- cytoplasm.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalCurrent Genetics
Volume19
Issue number4
DOIs
Publication statusPublished - Apr 1 1991

Keywords

  • Mistranslation
  • Yeast
  • ψ-factor

ASJC Scopus subject areas

  • Genetics

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    Ono, B. I., Chernoff, Y. O., Ishino-Arao, Y., Yamagishi, N., Shinoda, S., & Inge-Vechtomov, S. G. (1991). Interactions between chromosomal omnipotent suppressors and extrachromosomal effectors in Saccharomyces cerevisiae. Current Genetics, 19(4), 243-248. https://doi.org/10.1007/BF00355049