Interactions between chromosomal omnipotent suppressors and extrachromosomal effectors in Saccharomyces cerevisiae

Bun ichiro Ono, Yury O. Chernoff, Yumiko Ishino-Arao, Noriko Yamagishi, Sumio Shinoda, Sergey G. Inge-Vechtomov

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Chromosomal omnipotent suppressor mutations recovered in ψ+ strains of Saccharomyces cerevisiae were brought into ψ- cytoplasm. SUP46, SUP138 and SUP139 acted as dominant omnipotent suppressors in the ψ- cytoplasm though their suppressor activity was substantially reduced. SUP46 and SUP138 conferred recessive thermosensitivity and antibiotic sensitivity in ψ- cytoplasm as in ψ+ cytoplasm. On the other hand, sup111 through sup115, which acted as recessive omnipotent suppressors in the ψ+ cytoplasm, manifested no, or very low, suppressor activity in the ψ- cytoplasm. They, however, still enhanced the efficiency of the SUP29 tRNA suppressor in ψ- cytoplasm. A multicopy plasmid carrying the wild-type SUP35 gene enhanced the efficiency of sup111 in ψ- cytoplasm.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalCurrent Genetics
Volume19
Issue number4
DOIs
Publication statusPublished - Apr 1 1991

Keywords

  • Mistranslation
  • Yeast
  • ψ-factor

ASJC Scopus subject areas

  • Genetics

Fingerprint

Dive into the research topics of 'Interactions between chromosomal omnipotent suppressors and extrachromosomal effectors in Saccharomyces cerevisiae'. Together they form a unique fingerprint.

Cite this