Integral value of JT interval in magnetocardiography is sensitive to coronary stenosis and improves soon after coronary revascularization

Kei On, Shigeyuki Watanabe, Satsuki Yamada, Noriyuki Takeyasu, Yoshitsugu Nakagawa, Hidetaka Nishina, Takafumi Morimoto, Hideaki Aihara, Taizo Kimura, Yoko Sato, Keiji Tsukada, Akihiko Kandori, Tsuyoshi Miyashita, Kuniomi Ogata, Daisuke Suzuki, Iwao Yamaguchi, Kazutaka Aonuma

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Magnetocardiography (MCG) is sensitive to minute cardiac electric abnormalities, but its clinical utility in diagnosing ischemic heart disease (IHD) has not been established. The present study examined the usefulness of an integral MCG value of ventricular repolarization in patients with IHD. Methods and Results: MCG was performed at rest in 14 patients with coronary stenosis >75% confirmed by coronary angiography (IHD group) using a 64-channel system, and then the sum of the 64-channel integral values of the QRS or JT intervals (QRSi and JTi, respectively) was calculated. The JTi/QRSi value indicated the total power of currents in JT compared with those in QRS. These measurements were repeated within 2 weeks after coronary revascularization. The Control group comprised 30 healthy volunteers. The baseline value of JTi/QRSi was significantly smaller in the IHD than in the Control group, but after revascularization it increased and did not significantly differ from the Control group. No significant difference in ST deviation was identified by electrocardiography (ECG) before and after coronary revascularization. Analysis of the Control group revealed that JTi/QRSi was not affected by age. Conclusions: The JTi/QRSi of the MCG is more sensitive to coronary stenosis than ECG, and this parameter improves soon after coronary revascularization.

Original languageEnglish
Pages (from-to)1586-1592
Number of pages7
JournalCirculation Journal
Volume71
Issue number10
DOIs
Publication statusPublished - Oct 11 2007

Keywords

  • Coronary artery disease
  • Diagnosis
  • Mapping
  • Revascularization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    On, K., Watanabe, S., Yamada, S., Takeyasu, N., Nakagawa, Y., Nishina, H., Morimoto, T., Aihara, H., Kimura, T., Sato, Y., Tsukada, K., Kandori, A., Miyashita, T., Ogata, K., Suzuki, D., Yamaguchi, I., & Aonuma, K. (2007). Integral value of JT interval in magnetocardiography is sensitive to coronary stenosis and improves soon after coronary revascularization. Circulation Journal, 71(10), 1586-1592. https://doi.org/10.1253/circj.71.1586