Abstract
The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.
| Original language | English |
|---|---|
| Pages (from-to) | 1883-1886 |
| Number of pages | 4 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 80 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2016 |
Keywords
- Antiproliferative activity
- Apoptosis
- HeLa cells
- Taxanes
- Taxus chinensis var. Mairei
ASJC Scopus subject areas
- Analytical Chemistry
- Biotechnology
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry
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Cite this
Liu, H. S., Gao, Y. H., Liu, L. H., Liu, W., Shi, Q. W., Dong, M., Suzuki, T., & Kiyota, H. (2016). Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of hela cervical cancer cells. Bioscience, Biotechnology and Biochemistry, 80(10), 1883-1886. https://doi.org/10.1080/09168451.2016.1194182