Abstract
The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.
| Original language | English |
|---|---|
| Pages (from-to) | 1883-1886 |
| Number of pages | 4 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 80 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Antiproliferative activity
- Apoptosis
- HeLa cells
- Taxanes
- Taxus chinensis var. Mairei
ASJC Scopus subject areas
- Analytical Chemistry
- Biotechnology
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry
Cite this
Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of hela cervical cancer cells. / Liu, Hai Sheng; Gao, Yu Huan; Liu, Li Hong; Liu, Wei; Shi, Qing Wen; Dong, Mei; Suzuki, Toshikazu; Kiyota, Hiromasa.
In: Bioscience, Biotechnology and Biochemistry, Vol. 80, No. 10, 2016, p. 1883-1886.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of hela cervical cancer cells
AU - Liu, Hai Sheng
AU - Gao, Yu Huan
AU - Liu, Li Hong
AU - Liu, Wei
AU - Shi, Qing Wen
AU - Dong, Mei
AU - Suzuki, Toshikazu
AU - Kiyota, Hiromasa
PY - 2016
Y1 - 2016
N2 - The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.
AB - The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.
KW - Antiproliferative activity
KW - Apoptosis
KW - HeLa cells
KW - Taxanes
KW - Taxus chinensis var. Mairei
UR - http://www.scopus.com/inward/record.url?scp=84986294589&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84986294589&partnerID=8YFLogxK
U2 - 10.1080/09168451.2016.1194182
DO - 10.1080/09168451.2016.1194182
M3 - Article
C2 - 27296359
AN - SCOPUS:84986294589
VL - 80
SP - 1883
EP - 1886
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 10
ER -