Influence of prostaglandin E1* * Prostandin® - Prostagladin E1 - Ono Pharmaceutical Co. Ltd., Osaka, Japan. on proteinuria of diabetic nephropathy. A case report

Soji Okada, Yositugu Masaki, Hirofumi Makino, Kimiaki Sato, Toru Higuchi, Makoto Hiramatu, Zensuke Ota, Yooichiro Miyai, Yasuhisa Ogino, Kayo Takahasi

Research output: Contribution to journalArticle

Abstract

A case of a 57-year-old man who was admitted to hospital for the treatment of noninsulin dependent diabetes mellitus (NIDDM) and nephrosis is presented. Details of a full clinical and biochemical investigation are given. The patient was put on a diet of 1600 kcal per day and given Lente insulin to restore his fasting blood glucose to normal. Prostoglandin E1 was then given, 40 μg b.d. intravenously morning and evening to improve his creatintne clearance and reduce urinary protein successfully. Improvement in the nephrosis of diabetic retinopathy was ultimately attained in this one patient. He was discharged from hospital, has remained well for the past year, and able to do light work.

Original languageEnglish
Pages (from-to)263-266
Number of pages4
JournalClinical Trials Journal
Volume22
Issue number3
Publication statusPublished - Dec 1 1985

Keywords

  • Lente insulin
  • NIDDM
  • diet
  • nephrosis
  • prostaglandin E

ASJC Scopus subject areas

  • Pharmacology (medical)

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