TY - JOUR
T1 - INFANTILE MYOFIBROMATOSIS:Report of Two Cases
AU - Mizobuchi, Kohichi
AU - Yoshino, Tadashi
AU - Ikehara, Ikuko
AU - Kawabata, Kenji
AU - Tsutsumi, Akira
AU - Ogawa, Katsuo
AU - Saku, Takashi
PY - 1986/9
Y1 - 1986/9
N2 - Two cases of infantile myofibromatosis were presented. Case 1 was a 6‐month‐old girl with multiple nodular lesions in the left parietal bone, dermis of abdominal wall, chest wall, right upper arm, and bilateral femur. Case 2 was a 12‐month‐old girl with solitary nodular lesions in the left parietal bone having a tendency to enlarge. Histologically, these tumorous lesions consisted of broad bundles of well oriented spindle‐shaped cells superficially resembling smooth muscle tissue. In electron microscopy, the constituent cells combined ultrastructural characteristics of both fibroblasts and smooth muscle cells., Immunoperoxidase method showed that anti‐smooth muscle antibodies binded to the cytoplasm of the bundle forming cells. From these results, it may be concluded that the lesion consisted of pure proliferation of myofibroblasts, and its peculiar growth behavior was discussed, though the histogenesis still remains obscure. ACTA PATHOL. JPN. 36: 1411–1418, 1986.
AB - Two cases of infantile myofibromatosis were presented. Case 1 was a 6‐month‐old girl with multiple nodular lesions in the left parietal bone, dermis of abdominal wall, chest wall, right upper arm, and bilateral femur. Case 2 was a 12‐month‐old girl with solitary nodular lesions in the left parietal bone having a tendency to enlarge. Histologically, these tumorous lesions consisted of broad bundles of well oriented spindle‐shaped cells superficially resembling smooth muscle tissue. In electron microscopy, the constituent cells combined ultrastructural characteristics of both fibroblasts and smooth muscle cells., Immunoperoxidase method showed that anti‐smooth muscle antibodies binded to the cytoplasm of the bundle forming cells. From these results, it may be concluded that the lesion consisted of pure proliferation of myofibroblasts, and its peculiar growth behavior was discussed, though the histogenesis still remains obscure. ACTA PATHOL. JPN. 36: 1411–1418, 1986.
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U2 - 10.1111/j.1440-1827.1986.tb02863.x
DO - 10.1111/j.1440-1827.1986.tb02863.x
M3 - Article
C2 - 3788568
AN - SCOPUS:0023034573
VL - 36
SP - 1411
EP - 1418
JO - Pathology International
JF - Pathology International
SN - 1320-5463
IS - 9
ER -