Infantile myofibromatosis. Report of two cases

K. Mizobuchi, Tadashi Yoshino, I. Ikehara, K. Kawabata, A. Tsutsumi, K. Ogawa, T. Saku

Research output: Contribution to journalArticle

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Abstract

Two cases of infantile myofibromatosis were presented. Case 1 was a 6-month-old girl with multiple nodular lesions in the left parietal bone, dermis of abdominal wall, chest wall, right upper arm, and bilateral femur. Case 2 was a 12-month-old girl with solitary nodular lesions in the left parietal bone having a tendency to enlarge. Histologically, these tumorous lesions consisted of broad bundles of well oriented spindle-shaped cells superficially resembling smooth muscle tissue. In electron microscopy, the constituent cells combined ultrastructural characteristics of both fibroblasts and smooth muscle cells. Immunoperoxidase method showed that anti-smooth muscle antibodies binded to the cytoplasm of the bundle forming cells. From these results, it may be concluded that the lesion consisted of pure proliferation of myofibroblasts, and its peculiar growth behavior was discussed, though the histogenesis still remains obscure.

Original languageEnglish
Pages (from-to)1411-1418
Number of pages8
JournalActa Pathologica Japonica
Volume36
Issue number9
Publication statusPublished - 1986

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Parietal Bone
Smooth Muscle
Myofibroblasts
Abdominal Wall
Thoracic Wall
Dermis
Femur
Smooth Muscle Myocytes
Electron Microscopy
Cytoplasm
Arm
Fibroblasts
Muscles
Antibodies
Growth
Congenital Generalized Fibromatosis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Mizobuchi, K., Yoshino, T., Ikehara, I., Kawabata, K., Tsutsumi, A., Ogawa, K., & Saku, T. (1986). Infantile myofibromatosis. Report of two cases. Acta Pathologica Japonica, 36(9), 1411-1418.

Infantile myofibromatosis. Report of two cases. / Mizobuchi, K.; Yoshino, Tadashi; Ikehara, I.; Kawabata, K.; Tsutsumi, A.; Ogawa, K.; Saku, T.

In: Acta Pathologica Japonica, Vol. 36, No. 9, 1986, p. 1411-1418.

Research output: Contribution to journalArticle

Mizobuchi, K, Yoshino, T, Ikehara, I, Kawabata, K, Tsutsumi, A, Ogawa, K & Saku, T 1986, 'Infantile myofibromatosis. Report of two cases', Acta Pathologica Japonica, vol. 36, no. 9, pp. 1411-1418.
Mizobuchi K, Yoshino T, Ikehara I, Kawabata K, Tsutsumi A, Ogawa K et al. Infantile myofibromatosis. Report of two cases. Acta Pathologica Japonica. 1986;36(9):1411-1418.
Mizobuchi, K. ; Yoshino, Tadashi ; Ikehara, I. ; Kawabata, K. ; Tsutsumi, A. ; Ogawa, K. ; Saku, T. / Infantile myofibromatosis. Report of two cases. In: Acta Pathologica Japonica. 1986 ; Vol. 36, No. 9. pp. 1411-1418.
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