Induction of tributyltin-binding protein type 2 in Japanese flounder, Paralichthys olivaceus, by exposure to tributyltin-d27

Mohamed Nassef, Takahiko Tawaratsumita, Yumi Oba, Hina Satone, Kei Nakayama, Yohei Shimasaki, Tsuneo Honjo, Yuji Oshima

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7 Citations (Scopus)

Abstract

In this study, individual Japanese flounder were intraperitoneally injected with 2μg tributyltin-d27 (TBT-d27) fish-1. Blood samples were collected on day 7 after injection. TBT-binding protein types 1 and 2 (TBT-bp1, -bp2) in the blood serum were quantified by western blotting analysis. As a result, the concentration of TBT-bp2 in TBT-d27 treated group increased to 220% of that in the solvent control, whereas the TBT-bp1 concentration decreased to 65% of that in the solvent control. Additionally, a positive relationship between the concentrations of TBT-bp2 and TBT was observed in blood sera of wild and cultured flounder. We suggest that TBT-bp2 is produced in response to TBT exposure and may play an important role in fish physiology.

Original languageEnglish
Pages (from-to)412-414
Number of pages3
JournalMarine Pollution Bulletin
Volume62
Issue number2
DOIs
Publication statusPublished - Feb 1 2011

Keywords

  • Protein induction
  • Tributyltin-binding proteins

ASJC Scopus subject areas

  • Oceanography
  • Aquatic Science
  • Pollution

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    Nassef, M., Tawaratsumita, T., Oba, Y., Satone, H., Nakayama, K., Shimasaki, Y., Honjo, T., & Oshima, Y. (2011). Induction of tributyltin-binding protein type 2 in Japanese flounder, Paralichthys olivaceus, by exposure to tributyltin-d27. Marine Pollution Bulletin, 62(2), 412-414. https://doi.org/10.1016/j.marpolbul.2010.12.005