Increased synapsin I immunoreactivity during long-term potentiation in rat hippocampus

Keiko Sato; Kiyoshi Morimoto; Shuji Suemaru; Toshiki Sato; Norihito Yamada

doi:10.1016/S0006-8993(00)02460-4

Increased synapsin I immunoreactivity during long-term potentiation in rat hippocampus

Keiko Sato, Kiyoshi Morimoto, Shuji Suemaru, Toshiki Sato, Norihito Yamada

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

The level of synapsin I, a synaptic vesicle protein and marker for synaptic activation, was studied 8 h after long-term potentiation (LTP) induction in rat hippocampus in vivo. Quantitative immunohistochemical analysis revealed that synapsin I increased significantly in the molecular layer of the dentate gyrus and the stratum lucidum of CA3, suggesting activation of the granule cells by synaptic input to the dentate gyrus, and persistent enhancement of glutamate release from the axon terminals of the dentate granule cells. (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	219-222
Number of pages	4
Journal	Brain Research
Volume	872
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(00)02460-4
Publication status	Published - Jul 28 2000

Keywords

Hippocampus
Immunohistochemistry
Long-term potentiation
Quantitative analysis
Synapsin I

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(00)02460-4

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AU - Sato, Keiko

AU - Morimoto, Kiyoshi

AU - Suemaru, Shuji

AU - Sato, Toshiki

AU - Yamada, Norihito

PY - 2000/7/28

Y1 - 2000/7/28

N2 - The level of synapsin I, a synaptic vesicle protein and marker for synaptic activation, was studied 8 h after long-term potentiation (LTP) induction in rat hippocampus in vivo. Quantitative immunohistochemical analysis revealed that synapsin I increased significantly in the molecular layer of the dentate gyrus and the stratum lucidum of CA3, suggesting activation of the granule cells by synaptic input to the dentate gyrus, and persistent enhancement of glutamate release from the axon terminals of the dentate granule cells. (C) 2000 Elsevier Science B.V.

AB - The level of synapsin I, a synaptic vesicle protein and marker for synaptic activation, was studied 8 h after long-term potentiation (LTP) induction in rat hippocampus in vivo. Quantitative immunohistochemical analysis revealed that synapsin I increased significantly in the molecular layer of the dentate gyrus and the stratum lucidum of CA3, suggesting activation of the granule cells by synaptic input to the dentate gyrus, and persistent enhancement of glutamate release from the axon terminals of the dentate granule cells. (C) 2000 Elsevier Science B.V.

KW - Hippocampus

KW - Immunohistochemistry

KW - Long-term potentiation

KW - Quantitative analysis

KW - Synapsin I

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Increased synapsin I immunoreactivity during long-term potentiation in rat hippocampus

Abstract

Keywords

ASJC Scopus subject areas

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