Increased functional brain network efficiency during audiovisual temporal asynchrony integration task in aging

Bin Wang, Peizhen Li, Dandan Li, Yan Niu, Ting Yan, Ting Li, Rui Cao, Pengfei Yan, Yuxiang Guo, Weiping Yang, Yanna Ren, Xinrui Li, Fusheng Wang, Tianyi Yan, Jinglong Wu, Hui Zhang, Jie Xiang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Audiovisual integration significantly changes over the lifespan, but age-related functional connectivity in audiovisual temporal asynchrony integration tasks remains underexplored. In the present study, electroencephalograms (EEGs) of 27 young adults (22-25 years) and 25 old adults (61-76 years) were recorded during an audiovisual temporal asynchrony integration task with seven conditions [auditory (A), visual (V), AV, A50V, A100V, V50A and V100A]. We calculated the phase lag index (PLI)-weighted connectivity networks modulated by the audiovisual tasks and found that the PLI connections showed obvious dynamic changes after stimulus onset. In the theta (4-7 Hz) and alpha (8-13 Hz) bands, the AV and V50A conditions induced stronger functional connections and higher global and local efficiencies, reflecting a stronger audiovisual integration effect, which was attributed to the auditory information arriving at the primary auditory cortex earlier than the visual information reaching the primary visual cortex. Importantly, the functional connectivity and network efficiencies of old adults revealed higher global and local efficiencies and higher degree in both the theta and alpha bands. These larger network efficiencies indicated that old adults might experience more difficulties in attention and cognitive control during the audiovisual integration task with temporal asynchrony than young adults. There were significant associations between network efficiencies and peak time of integration only in young adults. We propose that an audiovisual task with multiple conditions might arouse the appropriate attention in young adults but would lead to a ceiling effect in old adults. Our findings provide new insights into the network topography of old adults during audiovisual integration and highlight higher functional connectivity and network efficiencies due to greater cognitive demand.

Original languageEnglish
Article number316
JournalFrontiers in Aging Neuroscience
Volume10
Issue numberOCT
DOIs
Publication statusPublished - Oct 9 2018

Fingerprint

Young Adult
Brain
Auditory Cortex
Visual Cortex
Electroencephalography

Keywords

  • Aging
  • Audiovisual integration
  • EEG
  • Functional connectivity
  • Theta and alpha bands

ASJC Scopus subject areas

  • Ageing
  • Cognitive Neuroscience

Cite this

Increased functional brain network efficiency during audiovisual temporal asynchrony integration task in aging. / Wang, Bin; Li, Peizhen; Li, Dandan; Niu, Yan; Yan, Ting; Li, Ting; Cao, Rui; Yan, Pengfei; Guo, Yuxiang; Yang, Weiping; Ren, Yanna; Li, Xinrui; Wang, Fusheng; Yan, Tianyi; Wu, Jinglong; Zhang, Hui; Xiang, Jie.

In: Frontiers in Aging Neuroscience, Vol. 10, No. OCT, 316, 09.10.2018.

Research output: Contribution to journalArticle

Wang, B, Li, P, Li, D, Niu, Y, Yan, T, Li, T, Cao, R, Yan, P, Guo, Y, Yang, W, Ren, Y, Li, X, Wang, F, Yan, T, Wu, J, Zhang, H & Xiang, J 2018, 'Increased functional brain network efficiency during audiovisual temporal asynchrony integration task in aging', Frontiers in Aging Neuroscience, vol. 10, no. OCT, 316. https://doi.org/10.3389/fnagi.2018.00316
Wang, Bin ; Li, Peizhen ; Li, Dandan ; Niu, Yan ; Yan, Ting ; Li, Ting ; Cao, Rui ; Yan, Pengfei ; Guo, Yuxiang ; Yang, Weiping ; Ren, Yanna ; Li, Xinrui ; Wang, Fusheng ; Yan, Tianyi ; Wu, Jinglong ; Zhang, Hui ; Xiang, Jie. / Increased functional brain network efficiency during audiovisual temporal asynchrony integration task in aging. In: Frontiers in Aging Neuroscience. 2018 ; Vol. 10, No. OCT.
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