Incorporation of Ca2+ ions in gelatin-siloxane hybrids through a sol-gel process

L. Ren, K. Tsuru, Satoshi Hayakawa, A. Osaka

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Several gelatin-siloxane hybrids incorporating Ca2+ ions were synthesized through a sol-gel process starting with gelatin, 3-(glycidoxypropyl) trimethoxysilane (GPSM), and Ca(NO3)2. Amino acid analysis, 29Si NMR spectroscopy, Fourier-transform infrared (FT-IR) spectroscopy, and dynamic mechanical thermal analysis were used to assess the hybrid structure. It has been indicated that the grafting degree of epoxy groups of GPSM to gelatin and the extent of polymerization of methoxysilane end groups of GPSM strongly depended on the fraction of GPSM (fG) in the hybrids, but not on incorporation of Ca2+ ions. Hence, the hybrids with the same fG value, independent of incorporation of Ca2+ ions, had a similar cross-link density. However, the glass transition temperature (Tg) and storage modulus (E′) around Tg decreased with incorporation of Ca2+ ions. Through the deconvolution of amide I bands of FT-IR spectra, flexibility may be interpreted by that the percentage of gelatin having a random structure increased with incorporation of Ca2+ ions. The Ca2+-containing hybrids can spontaneously deposit apatite when they were soaked in a simulated body fluid of the Kokubo recipe, showing their bioactivity.

Original languageEnglish
Pages (from-to)406-411
Number of pages6
JournalNippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
Volume109
Issue number1269
Publication statusPublished - May 2001

Fingerprint

Siloxanes
siloxanes
gelatins
Gelatin
sol-gel processes
Sol-gel process
Ions
ions
Apatites
hybrid structures
body fluids
Body fluids
Apatite
Deconvolution
apatites
Bioactivity
Amides
glass transition temperature
Thermoanalysis
amides

Keywords

  • 3-(glycidoxypropyl) trimethoxysilane
  • Gelatin
  • Hybrid
  • In vitro bioactivity
  • Sol-gel

ASJC Scopus subject areas

  • Ceramics and Composites

Cite this

Incorporation of Ca2+ ions in gelatin-siloxane hybrids through a sol-gel process. / Ren, L.; Tsuru, K.; Hayakawa, Satoshi; Osaka, A.

In: Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan, Vol. 109, No. 1269, 05.2001, p. 406-411.

Research output: Contribution to journalArticle

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