Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol

Shizuo Narimatsu, Takayuki Arai, Yasuhiro Masubuchi, Toshiharu Horie, Masakiyo Hosokawa, Koichi Ueno, Hiroyuki Kataoka, Shigeo Yamamoto, Tsutomu Ishikawa, Arthur K. Cho

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Medicine & Life Sciences