In Vivo Response of Osteoblast-like and Odontoblast-like Cells in Intraperitoneal Diffusion Chamber

Andrea Paola Rodriguez, Hidetsugu Tsujigiwa, Hitoshi Nagatsuka, Kazuo Ichikawa, Noriyuki Nagai, Atsuhisa Minonishi, Missana Liliana, C. L. Qin

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Preliminary analysis of cells before using them in tissue engineering is mandatory. Thus, to clarify the behavior of cells in an appropriate experimental model, we evaluated the characteristic of MDPC-23 cells and KUSA/A1 cells in vitro and in vivo seeded in diffusion chamber. Our results indicated that KUSA/A1 cells differentiated into osteoblast-like cells and induced bone tissue inside the chamber. Whereas, MDPC-23 cells were odontoblast-like cells but with low ability to induce dentin formation. This study suggests that MDPC-23 cells are special cells, which possess morphological and functional character of odontoblast-like cells, expressing DSPP only in vivo with low capacity to induce mineralized dentin matrix.

Original languageEnglish
Pages (from-to)294-295
Number of pages2
JournalJournal of Hard Tissue Biology
Volume14
Issue number2
DOIs
Publication statusPublished - Jan 2005

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • Dentistry(all)
  • Cell Biology

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    Rodriguez, A. P., Tsujigiwa, H., Nagatsuka, H., Ichikawa, K., Nagai, N., Minonishi, A., Liliana, M., & Qin, C. L. (2005). In Vivo Response of Osteoblast-like and Odontoblast-like Cells in Intraperitoneal Diffusion Chamber. Journal of Hard Tissue Biology, 14(2), 294-295. https://doi.org/10.2485/jhtb.14.294