Abstract
This chapter discusses in vitro degradation behaviors of calcium phosphate particles, such as nano-crystalline hydroxyapatite (HAp) and ion-substituted HAp synthesized by the wet-chemical processing method, and how their microstructure affects their initial dissolution profiles and kinetics. The chapter reviews several in vitro evaluation techniques for biodegradability of calcium phosphate ceramics and several models representing dissolution profiles and kinetics. The chapter then discusses the relationship between the heterogeneous structure of nano-crystalline HAp and the initial dissolution behaviors in acidic buffer solution.
| Original language | English |
|---|---|
| Title of host publication | Hydroxyapatite (HAp) for Biomedical Applications |
| Publisher | Elsevier Ltd |
| Pages | 85-105 |
| Number of pages | 21 |
| ISBN (Print) | 9781782420415, 9781782420330 |
| DOIs | |
| Publication status | Published - Feb 27 2015 |
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Keywords
- Amorphous phase
- Biodegradation
- Calcium phosphate
- Disordered phase
- Dissolution kinetics
- Dissolution rate
- Hydroxyapatite
- In vitro degradation
- Ionic substitution
- Nano-crystal
ASJC Scopus subject areas
- Engineering(all)
- Materials Science(all)
Cite this
In vitro degradation behavior of hydroxyapatite. / Hayakawa, Satoshi.
Hydroxyapatite (HAp) for Biomedical Applications. Elsevier Ltd, 2015. p. 85-105.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - In vitro degradation behavior of hydroxyapatite
AU - Hayakawa, Satoshi
PY - 2015/2/27
Y1 - 2015/2/27
N2 - This chapter discusses in vitro degradation behaviors of calcium phosphate particles, such as nano-crystalline hydroxyapatite (HAp) and ion-substituted HAp synthesized by the wet-chemical processing method, and how their microstructure affects their initial dissolution profiles and kinetics. The chapter reviews several in vitro evaluation techniques for biodegradability of calcium phosphate ceramics and several models representing dissolution profiles and kinetics. The chapter then discusses the relationship between the heterogeneous structure of nano-crystalline HAp and the initial dissolution behaviors in acidic buffer solution.
AB - This chapter discusses in vitro degradation behaviors of calcium phosphate particles, such as nano-crystalline hydroxyapatite (HAp) and ion-substituted HAp synthesized by the wet-chemical processing method, and how their microstructure affects their initial dissolution profiles and kinetics. The chapter reviews several in vitro evaluation techniques for biodegradability of calcium phosphate ceramics and several models representing dissolution profiles and kinetics. The chapter then discusses the relationship between the heterogeneous structure of nano-crystalline HAp and the initial dissolution behaviors in acidic buffer solution.
KW - Amorphous phase
KW - Biodegradation
KW - Calcium phosphate
KW - Disordered phase
KW - Dissolution kinetics
KW - Dissolution rate
KW - Hydroxyapatite
KW - In vitro degradation
KW - Ionic substitution
KW - Nano-crystal
UR - http://www.scopus.com/inward/record.url?scp=84940025704&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84940025704&partnerID=8YFLogxK
U2 - 10.1016/B978178242033000004-3
DO - 10.1016/B978178242033000004-3
M3 - Chapter
AN - SCOPUS:84940025704
SN - 9781782420415
SN - 9781782420330
SP - 85
EP - 105
BT - Hydroxyapatite (HAp) for Biomedical Applications
PB - Elsevier Ltd
ER -