In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

Lei Ren, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka

Research output: Contribution to journalArticle

Abstract

Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

Original languageEnglish
Pages (from-to)CC10.6.1-CC10.6.6
JournalMaterials Research Society Symposium - Proceedings
Volume628
Publication statusPublished - 2000

Fingerprint

biodegradation
Silicates
Apatites
gelatins
Apatite
apatites
Gelatin
sol-gel processes
Biodegradation
Sol-gel process
bones
silicates
Bone
porosity
freeze drying
Tromethamine
body fluids
tissue engineering
Body fluids
Scaffolds (biology)

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. / Ren, Lei; Tsuru, Kanji; Hayakawa, Satoshi; Osaka, Akiyoshi.

In: Materials Research Society Symposium - Proceedings, Vol. 628, 2000, p. CC10.6.1-CC10.6.6.

Research output: Contribution to journalArticle

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