In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

L. Ren, K. Tsuru, Satoshi Hayakawa, A. Osaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

Original languageEnglish
Title of host publicationMaterials Research Society Symposium - Proceedings
EditorsR.M. Laine, C. Sanchez, C.J. Brinker, E. Giannelis
Volume628
Publication statusPublished - 2000
EventOrganic/Inorganic Hybrid Materials-2000 - San Francisco, CA, United States
Duration: Apr 24 2000Apr 28 2000

Other

OtherOrganic/Inorganic Hybrid Materials-2000
CountryUnited States
CitySan Francisco, CA
Period4/24/004/28/00

Fingerprint

Silicates
Apatites
Apatite
Gelatin
Biodegradation
Sol-gel process
Bone
Tromethamine
Body fluids
Scaffolds (biology)
Tissue engineering
Temperature control
Freezing
Pore size
Sol-gels
Drying
Porosity
Processing
trimethoxysilane

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Ren, L., Tsuru, K., Hayakawa, S., & Osaka, A. (2000). In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. In R. M. Laine, C. Sanchez, C. J. Brinker, & E. Giannelis (Eds.), Materials Research Society Symposium - Proceedings (Vol. 628)

In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. / Ren, L.; Tsuru, K.; Hayakawa, Satoshi; Osaka, A.

Materials Research Society Symposium - Proceedings. ed. / R.M. Laine; C. Sanchez; C.J. Brinker; E. Giannelis. Vol. 628 2000.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ren, L, Tsuru, K, Hayakawa, S & Osaka, A 2000, In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. in RM Laine, C Sanchez, CJ Brinker & E Giannelis (eds), Materials Research Society Symposium - Proceedings. vol. 628, Organic/Inorganic Hybrid Materials-2000, San Francisco, CA, United States, 4/24/00.
Ren L, Tsuru K, Hayakawa S, Osaka A. In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. In Laine RM, Sanchez C, Brinker CJ, Giannelis E, editors, Materials Research Society Symposium - Proceedings. Vol. 628. 2000
Ren, L. ; Tsuru, K. ; Hayakawa, Satoshi ; Osaka, A. / In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process. Materials Research Society Symposium - Proceedings. editor / R.M. Laine ; C. Sanchez ; C.J. Brinker ; E. Giannelis. Vol. 628 2000.
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