Abstract
The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.
| Original language | English |
|---|---|
| Pages (from-to) | 121-130 |
| Number of pages | 10 |
| Journal | BUNSEKI KAGAKU |
| Volume | 62 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2013 |
Keywords
- In situ monitoring
- Ion sensor
- Membrane-active drug
- Oxygen electrode
- Photoinactivation
ASJC Scopus subject areas
- Analytical Chemistry
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Katsu, T., Komagoe, K., Masuda, K., Kato, H., & Inoue, T. (2013). In situ monitoring of drug action using sensors. BUNSEKI KAGAKU, 62(2), 121-130. https://doi.org/10.2116/bunsekikagaku.62.121