In situ monitoring of drug action using sensors

Takashi Katsu; Keiko Komagoe; Kazufumi Masuda; Hisato Kato; Tsuyoshi Inoue

doi:10.2116/bunsekikagaku.62.121

In situ monitoring of drug action using sensors

Takashi Katsu, Keiko Komagoe, Kazufumi Masuda, Hisato Kato, Tsuyoshi Inoue

Research output: Contribution to journal › Article › peer-review

Abstract

The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K⁺ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.

Original language	English
Pages (from-to)	121-130
Number of pages	10
Journal	BUNSEKI KAGAKU
Volume	62
Issue number	2
DOIs	https://doi.org/10.2116/bunsekikagaku.62.121
Publication status	Published - 2013

Keywords

In situ monitoring
Ion sensor
Membrane-active drug
Oxygen electrode
Photoinactivation

ASJC Scopus subject areas

Analytical Chemistry

Access to Document

10.2116/bunsekikagaku.62.121

Fingerprint Dive into the research topics of 'In situ monitoring of drug action using sensors'. Together they form a unique fingerprint.

Cite this

@article{d496495d0c364d93a640cd2fa3bc8214,

title = "In situ monitoring of drug action using sensors",

abstract = "The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.",

keywords = "In situ monitoring, Ion sensor, Membrane-active drug, Oxygen electrode, Photoinactivation",

author = "Takashi Katsu and Keiko Komagoe and Kazufumi Masuda and Hisato Kato and Tsuyoshi Inoue",

year = "2013",

doi = "10.2116/bunsekikagaku.62.121",

language = "English",

volume = "62",

pages = "121--130",

journal = "Bunseki Kagaku",

issn = "0525-1931",

publisher = "Japan Society for Analytical Chemistry",

number = "2",

}

TY - JOUR

T1 - In situ monitoring of drug action using sensors

AU - Katsu, Takashi

AU - Komagoe, Keiko

AU - Masuda, Kazufumi

AU - Kato, Hisato

AU - Inoue, Tsuyoshi

PY - 2013

Y1 - 2013

N2 - The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.

AB - The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.

KW - In situ monitoring

KW - Ion sensor

KW - Membrane-active drug

KW - Oxygen electrode

KW - Photoinactivation

UR - http://www.scopus.com/inward/record.url?scp=84946163849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84946163849&partnerID=8YFLogxK

U2 - 10.2116/bunsekikagaku.62.121

DO - 10.2116/bunsekikagaku.62.121

M3 - Article

AN - SCOPUS:84946163849

VL - 62

SP - 121

EP - 130

JO - Bunseki Kagaku

JF - Bunseki Kagaku

SN - 0525-1931

IS - 2

ER -

In situ monitoring of drug action using sensors

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this