Abstract
The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.
| Original language | English |
|---|---|
| Pages (from-to) | 121-130 |
| Number of pages | 10 |
| Journal | Bunseki Kagaku |
| Volume | 62 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2013 |
Fingerprint
Keywords
- In situ monitoring
- Ion sensor
- Membrane-active drug
- Oxygen electrode
- Photoinactivation
ASJC Scopus subject areas
- Analytical Chemistry
Cite this
In situ monitoring of drug action using sensors. / Katsu, Takashi; Komagoe, Keiko; Masuda, Kazufumi; Kato, Hisato; Inoue, Tsuyoshi.
In: Bunseki Kagaku, Vol. 62, No. 2, 2013, p. 121-130.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - In situ monitoring of drug action using sensors
AU - Katsu, Takashi
AU - Komagoe, Keiko
AU - Masuda, Kazufumi
AU - Kato, Hisato
AU - Inoue, Tsuyoshi
PY - 2013
Y1 - 2013
N2 - The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.
AB - The application of electrochemical sensors to biochemical analysis is attractive, because the measurement is fast, easy, and continuous in a turbid cell suspension. In addition, the apparatus used is inexpensive. In this paper, we report on how electrochemical sensors, such as oxygen electrode and ion sensors, are useful to analyze the photoinactivation of bacteria induced by dyes. Furthermore, we coupled a K+ sensor with spectrometry. This methodology enabled us to rapidly screen the sizes of pores formed in a liposomal membrane. We also describe a simple method for constructing ion sensors in a laboratory.
KW - In situ monitoring
KW - Ion sensor
KW - Membrane-active drug
KW - Oxygen electrode
KW - Photoinactivation
UR - http://www.scopus.com/inward/record.url?scp=84946163849&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84946163849&partnerID=8YFLogxK
U2 - 10.2116/bunsekikagaku.62.121
DO - 10.2116/bunsekikagaku.62.121
M3 - Article
AN - SCOPUS:84946163849
VL - 62
SP - 121
EP - 130
JO - Bunseki Kagaku
JF - Bunseki Kagaku
SN - 0525-1931
IS - 2
ER -