Improved synthesis and crystal structure of TiCl3(tmeda)(thf)

A highly stereoselective pinacol coupling reagent for aromatic aldehydes

Toshiyuki Oshiki, Takayuki Kiriyama, Kazuaki Tsuchida, Kazuhiko Takai

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A monomeric titanium(III) complex, TiCl3(tmeda)(thf) (1), has been prepared by a reaction of TiCl4 with TMEDA, Zn, and a catalytic amount of PbCl2 in an almost quantitative yield. The solid state structure of 1 is revealed by X-ray crystallographic analysis. The complex 1 couples aromatic aldehydes under mild conditions to give 1,2-diols in good to excellent yields with high d/-selectivities.

Original languageEnglish
Pages (from-to)334-335
Number of pages2
JournalChemistry Letters
Issue number4
Publication statusPublished - 2000

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Titanium
Aldehydes
Crystal structure
X rays
lead chloride
titanium tetrachloride
titanium trichloride
phenyllithium

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Improved synthesis and crystal structure of TiCl3(tmeda)(thf) : A highly stereoselective pinacol coupling reagent for aromatic aldehydes. / Oshiki, Toshiyuki; Kiriyama, Takayuki; Tsuchida, Kazuaki; Takai, Kazuhiko.

In: Chemistry Letters, No. 4, 2000, p. 334-335.

Research output: Contribution to journalArticle

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