Improved syntheses of d-ribo- and 2-deoxy-d-ribofuranose phospho sugars from methyl β-d-ribopyranoside

Tadashi Hanaya, Yuko Koga, Heizan Kawamoto, Hiroshi Yamamoto

Research output: Contribution to journalArticle

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Abstract

Abstract - Methyl 4-deoxy-4-dimethoxyphosphinoyl-2,3-O-isopropylidene-13-D-ribopyranoside (12a) and methyl 2,4-dideoxy-4-dimethoxyphosphinoyl-13-D-etythro-pentopyranoside (20) were efficiently prepared respectively from methyl2,3-O-isopropylidene-[3-D-ribopyranoside (7a) and its 3,4-O-isopropylideneisomer (7b) in appreciably improved total yields compared with those via previously reported routes.Compounds (12a, 20) were led to D-ribofuranos and 2-deoxy-D-ribofuranose phospho sugars (4, 5).

Original languageEnglish
Pages (from-to)581-591
Number of pages11
JournalHeterocycles
Volume73
Issue numberC
DOIs
Publication statusPublished - 2007

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Sugars
propylene
compound 20

ASJC Scopus subject areas

  • Organic Chemistry

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Improved syntheses of d-ribo- and 2-deoxy-d-ribofuranose phospho sugars from methyl β-d-ribopyranoside. / Hanaya, Tadashi; Koga, Yuko; Kawamoto, Heizan; Yamamoto, Hiroshi.

In: Heterocycles, Vol. 73, No. C, 2007, p. 581-591.

Research output: Contribution to journalArticle

Hanaya, Tadashi ; Koga, Yuko ; Kawamoto, Heizan ; Yamamoto, Hiroshi. / Improved syntheses of d-ribo- and 2-deoxy-d-ribofuranose phospho sugars from methyl β-d-ribopyranoside. In: Heterocycles. 2007 ; Vol. 73, No. C. pp. 581-591.
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AU - Kawamoto, Heizan

AU - Yamamoto, Hiroshi

PY - 2007

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