Abstract
Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.
| Original language | English |
|---|---|
| Pages (from-to) | 2097-2099 |
| Number of pages | 3 |
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy |
| Volume | 32 |
| Issue number | 13 |
| Publication status | Published - Dec 2005 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Cancer Research
- Pharmacology
Cite this
Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel. / Kubo, Masatoshi; Jida, Masaru; Yamane, Masaomi; Miyatani, Katsuya; Udaka, Tetsunobu; Sogabe, Osanori; Maeda, Hiroya; Mizuta, Minoru; Shirakawa, Kazutoyo.
In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 32, No. 13, 12.2005, p. 2097-2099.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel
AU - Kubo, Masatoshi
AU - Jida, Masaru
AU - Yamane, Masaomi
AU - Miyatani, Katsuya
AU - Udaka, Tetsunobu
AU - Sogabe, Osanori
AU - Maeda, Hiroya
AU - Mizuta, Minoru
AU - Shirakawa, Kazutoyo
PY - 2005/12
Y1 - 2005/12
N2 - Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.
AB - Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.
UR - http://www.scopus.com/inward/record.url?scp=33644686180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33644686180&partnerID=8YFLogxK
M3 - Article
C2 - 16352935
AN - SCOPUS:33644686180
VL - 32
SP - 2097
EP - 2099
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 13
ER -