Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel

Masatoshi Kubo; Masaru Jida; Masaomi Yamane; Katsuya Miyatani; Tetsunobu Udaka; Osanori Sogabe; Hiroya Maeda; Minoru Mizuta; Kazutoyo Shirakawa

Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel

Masatoshi Kubo, Masaru Jida, Masaomi Yamane, Katsuya Miyatani, Tetsunobu Udaka, Osanori Sogabe, Hiroya Maeda, Minoru Mizuta, Kazutoyo Shirakawa

Research output: Contribution to journal › Article › peer-review

Abstract

Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.

Original language	English
Pages (from-to)	2097-2099
Number of pages	3
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	32
Issue number	13
Publication status	Published - Dec 2005
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel. / Kubo, Masatoshi; Jida, Masaru; Yamane, Masaomi; Miyatani, Katsuya; Udaka, Tetsunobu; Sogabe, Osanori; Maeda, Hiroya; Mizuta, Minoru; Shirakawa, Kazutoyo.

In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 32, No. 13, 12.2005, p. 2097-2099.

Research output: Contribution to journal › Article › peer-review

Kubo, Masatoshi ; Jida, Masaru ; Yamane, Masaomi ; Miyatani, Katsuya ; Udaka, Tetsunobu ; Sogabe, Osanori ; Maeda, Hiroya ; Mizuta, Minoru ; Shirakawa, Kazutoyo. / Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel. In: Gan to kagaku ryoho. Cancer & chemotherapy. 2005 ; Vol. 32, No. 13. pp. 2097-2099.

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title = "Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel",

abstract = "Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.",

author = "Masatoshi Kubo and Masaru Jida and Masaomi Yamane and Katsuya Miyatani and Tetsunobu Udaka and Osanori Sogabe and Hiroya Maeda and Minoru Mizuta and Kazutoyo Shirakawa",

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AU - Jida, Masaru

AU - Yamane, Masaomi

AU - Miyatani, Katsuya

AU - Udaka, Tetsunobu

AU - Sogabe, Osanori

AU - Maeda, Hiroya

AU - Mizuta, Minoru

AU - Shirakawa, Kazutoyo

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AB - Carcinomatous meningitis from breast cancer is rare and has a poor prognosis with a life expectancy of approximately 80 days. We performed intrathecal MTX and Ara-C in combination with systemic docetaxel treatments in the patient, a 44-year-old woman with carcinomatous meningitis from invasive lobular carcinoma previously treated with anthracycline and paclitaxel. Although the patient died 128 days after the onset, intrathecal chemotherapy in combination with systemic docetaxel reduced the number of malignant cells and induced degeneration of the cells in CSF, resulting in improved quality of life.

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