Impact of spontaneous anterograde flow of the infarct artery on left ventricular function in patients with a first anterior wall acute myocardial infarction

Masaharu Ishihara, Ichiro Inoue, Takuji Kawagoe, Yuji Shimatani, Satoshi Kurisu, Kenji Nishioka, Takashi Umemura, Shuji Nakamura, Masashi Yoshida

Research output: Contribution to journalArticle

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Abstract

To assess the impact of spontaneous anterograde flow of the infarct artery on outcomes in patients with acute myocardial infarction (AMI), we studied 478 patients with a first anterior wall AMI who underwent coronary angiography within 12 hours after the onset of chest pain; Thrombolysis In Myocardial Infarction (TIMI) 3 flow was obtained after reperfusion therapy. Patients were divided into 3 groups: 119 patients with spontaneous anterograde flow (initial TIMI 2 or 3 flow) of the infarct artery, 118 patients with an initially occluded artery (TIMI 0 or 1 flow) and time to angiography ≤2 hours (very early reperfusion), and 241 patients with an initially occluded artery and time to angiography of 2 to 12 hours (late reperfusion). Acute left ventricular (LV) ejection fraction (EF) was significantly higher in patients with spontaneous anterograde flow than in patients without (54 ± 14% vs 47 ± 10%, p

Original languageEnglish
Pages (from-to)5-9
Number of pages5
JournalAmerican Journal of Cardiology
Volume90
Issue number1
DOIs
Publication statusPublished - Jul 1 2002
Externally publishedYes

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Anterior Wall Myocardial Infarction
Left Ventricular Function
Arteries
Myocardial Infarction
Reperfusion
Angiography
Coronary Angiography
Chest Pain
Stroke Volume

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Impact of spontaneous anterograde flow of the infarct artery on left ventricular function in patients with a first anterior wall acute myocardial infarction. / Ishihara, Masaharu; Inoue, Ichiro; Kawagoe, Takuji; Shimatani, Yuji; Kurisu, Satoshi; Nishioka, Kenji; Umemura, Takashi; Nakamura, Shuji; Yoshida, Masashi.

In: American Journal of Cardiology, Vol. 90, No. 1, 01.07.2002, p. 5-9.

Research output: Contribution to journalArticle

Ishihara, Masaharu ; Inoue, Ichiro ; Kawagoe, Takuji ; Shimatani, Yuji ; Kurisu, Satoshi ; Nishioka, Kenji ; Umemura, Takashi ; Nakamura, Shuji ; Yoshida, Masashi. / Impact of spontaneous anterograde flow of the infarct artery on left ventricular function in patients with a first anterior wall acute myocardial infarction. In: American Journal of Cardiology. 2002 ; Vol. 90, No. 1. pp. 5-9.
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