Abstract
Aim: The purpose of this study was to determine the relationship between the combined presence of medial temporal atrophy (MTA) and white matter lesions (WMLs: periventricular hyperintensity (PVH) and deep white matter hyperintensity) and the cognitive/emotional function in Alzheimer’s disease (AD) patients. Methods: The subjects included 193 patients with AD and 30 normal elderly controls. On MRI, MTA was rated using the Voxel-based specific regional analysis system for AD (VSRAD). WMLs was also estimated using the Fazekas scale. The MRI measurements were classified as follows: MTA = VSRAD***p**p*p*p*p*p
| Original language | English |
|---|---|
| Pages (from-to) | 342-349 |
| Number of pages | 8 |
| Journal | Japanese Journal of Geriatrics |
| Volume | 51 |
| Issue number | 4 |
| Publication status | Published - 2014 |
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Keywords
- Alzheimer's disease
- Cognitive function
- Emotional function
- Medial temporal atrophy
- White matter lesion
ASJC Scopus subject areas
- Geriatrics and Gerontology
Cite this
Impact of combined medial temporal atrophy and white matter lesions on the cognitive and emotional functions in Alzheimer's disease patients. / Tokuchi, Ryou; Deguchi, Kentaro; Yamashita, Toru; Abe, Koji.
In: Japanese Journal of Geriatrics, Vol. 51, No. 4, 2014, p. 342-349.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Impact of combined medial temporal atrophy and white matter lesions on the cognitive and emotional functions in Alzheimer's disease patients
AU - Tokuchi, Ryou
AU - Deguchi, Kentaro
AU - Yamashita, Toru
AU - Abe, Koji
PY - 2014
Y1 - 2014
N2 - Aim: The purpose of this study was to determine the relationship between the combined presence of medial temporal atrophy (MTA) and white matter lesions (WMLs: periventricular hyperintensity (PVH) and deep white matter hyperintensity) and the cognitive/emotional function in Alzheimer’s disease (AD) patients. Methods: The subjects included 193 patients with AD and 30 normal elderly controls. On MRI, MTA was rated using the Voxel-based specific regional analysis system for AD (VSRAD). WMLs was also estimated using the Fazekas scale. The MRI measurements were classified as follows: MTA = VSRAD***p**p*p*p*p*p
AB - Aim: The purpose of this study was to determine the relationship between the combined presence of medial temporal atrophy (MTA) and white matter lesions (WMLs: periventricular hyperintensity (PVH) and deep white matter hyperintensity) and the cognitive/emotional function in Alzheimer’s disease (AD) patients. Methods: The subjects included 193 patients with AD and 30 normal elderly controls. On MRI, MTA was rated using the Voxel-based specific regional analysis system for AD (VSRAD). WMLs was also estimated using the Fazekas scale. The MRI measurements were classified as follows: MTA = VSRAD***p**p*p*p*p*p
KW - Alzheimer's disease
KW - Cognitive function
KW - Emotional function
KW - Medial temporal atrophy
KW - White matter lesion
UR - http://www.scopus.com/inward/record.url?scp=84908099233&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908099233&partnerID=8YFLogxK
M3 - Article
C2 - 25327368
AN - SCOPUS:84908099233
VL - 51
SP - 342
EP - 349
JO - Japanese Journal of Geriatrics
JF - Japanese Journal of Geriatrics
SN - 0300-9173
IS - 4
ER -