Immunological studies of uveitis. 1. Immune complex containing herpes virus antigens in four patients with acute retinal necrosis syndrome

T. Matsuo, T. Nakayama, N. Matsuo, N. Koide

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Abstract

Four patients with acute retinal necrosis syndrome were examined. Three of them showed elevated antibody titers to varicella-zoster virus during the convalescent stage, while one of them showed an elevated titer to herpes simplex virus type 1, especially in the intraocular fluid. Also, these patients had an elevated circulating immune complex in the acute phase. Western blotting demonstrated that the immune complexes containing varicella-zoster or herpes simplex type 1 antigen, corresponding to the elevated antibody titer to either virus.

Original languageEnglish
Pages (from-to)472-479
Number of pages8
JournalJapanese Journal of Ophthalmology
Volume30
Issue number4
Publication statusPublished - Dec 1 1986

ASJC Scopus subject areas

  • Ophthalmology

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