Immunological responses to Candida albicans in patients with bronchial asthma and its relationship to patient age

Yoshiro Tanizaki, Hikaru Kitani, Morihiro Okazaki, Takashi Mifune, Fumihiro Mitsunobu, Naoki Kotoh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The release of histamine induced by C. albicans was significantly higher in asthmatics aged 21-30 yr, 41-50 yr and 61+ years old compared with the age-matched groups of healthy subjects. The level of C. albicans specific IgG was significantly higher in asthmatics aged 41 -50 years old compared with age-matched group of healthy subjects. No significant difference was found among any age groups of healthy and asthmatic subjects. The increased level of C. albicans specific IgG seemed not to be of significance in the pathogenesis of asthma.

Original languageEnglish
Pages (from-to)162-167
Number of pages6
JournalJapanese Journal of Clinical Immunology
Volume15
Issue number2
DOIs
Publication statusPublished - 1992

Keywords

  • aging
  • basophil histamine release
  • Bronchial asthma
  • Candida albicans specific IgG

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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