Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens

M. Motoi, Tadashi Yoshino, K. Hayashi, S. Nose, Y. Horie, K. Ogawa

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Using the four-step peroxidase-antiper-oxidase (PAP) method, the presence of the antigen recognized with anti-Leu 7 monoclonal antibody was investigated in paraffin-embedded human brain tissue and tumors. The antigen was demonstrated in the myelin sheaths, oligodendrocytes, and some choroid plexus cells in normal brain and in oligodendrogliomas, some astrocytomas and choroid plexus papillomas. The technique can be used to identify hormal and neoplastic oligodendrocytes.

Original languageEnglish
Pages (from-to)75-77
Number of pages3
JournalActa Neuropathologica
Volume66
Issue number1
DOIs
Publication statusPublished - Mar 1985

Fingerprint

Oligodendroglia
Brain Neoplasms
Paraffin
Choroid Plexus Papilloma
Monoclonal Antibodies
Oligodendroglioma
Antigens
Choroid Plexus
Astrocytoma
Myelin Sheath
Peroxidase
Oxidoreductases
Brain

Keywords

  • Anti-Leu 7
  • Four-step PAP method
  • Oligodendroglioma

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens. / Motoi, M.; Yoshino, Tadashi; Hayashi, K.; Nose, S.; Horie, Y.; Ogawa, K.

In: Acta Neuropathologica, Vol. 66, No. 1, 03.1985, p. 75-77.

Research output: Contribution to journalArticle

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