Immunohistochemical observation of HSP27 in ameloblastomas

Muneteru Fujita, Keisuke Nakano, Hatsuhiko Maeda, Waka Yoshida, Ryota Torii, Masanori Yoshiyama, Norimasa Okafuji, Hiromasa Hasegawa, Toshiyuki Kawakami

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We examined expression of Heat Shock Protein 27 (HSP27) molecules, in 10 cases of typical solid/ multicystic ameloblastoma, by means of immunohistochemistry. In general, HSP27 and pHSP27 positive staining products were frequently detected in the cytoplasms of the neoplastic cells. The expression pattern and/or strength are slightly different according to the cytological features of ameloblastomas. The immunohistochemical staining results suggest that the expression of HSP27 and pHSP27 is considered to be involved in neoplastic transformation of odontogenic epithelial cells.

Original languageEnglish
Pages (from-to)289-294
Number of pages6
JournalJournal of Hard Tissue Biology
Volume20
Issue number4
DOIs
Publication statusPublished - Dec 1 2011
Externally publishedYes

Keywords

  • Ameloblastoma
  • HSP27
  • Heat shock protein 27
  • Immunohistochemistry

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • Dentistry(all)
  • Cell Biology

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  • Cite this

    Fujita, M., Nakano, K., Maeda, H., Yoshida, W., Torii, R., Yoshiyama, M., Okafuji, N., Hasegawa, H., & Kawakami, T. (2011). Immunohistochemical observation of HSP27 in ameloblastomas. Journal of Hard Tissue Biology, 20(4), 289-294. https://doi.org/10.2485/jhtb.20.289