Immunohistochemical observation of BMP in the mouse orthodontic periodontal tension sides

Hirokazu Matsuda, Rina Muraoka, Maki Tomoda, Keisuke Nakano, Norimasa Okafuji, Kazuhiro Yamada, Toshiyuki Kawakami

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The purpose of this examination was to in vestigate the expression of BMP-2 and -4 in mouse orthodontic periodontal tension sides exposed orthodontic mechanical stress using the method of Waldo. Immnohistochemically, in the experimental group, strong expression of BMP-2 and -4 were observed in the periodontal tension sides at 20minutes. The results strongly suggested that the BMP-2 and -4 promoted the Runx2 expression for osteoblastic differention in the orthodontic periodontal tension sides at the early stage after receiving of the mechanical stress.

Original languageEnglish
Pages (from-to)181-184
Number of pages4
JournalJournal of Hard Tissue Biology
Volume18
Issue number4
DOIs
Publication statusPublished - Mar 23 2010
Externally publishedYes

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Orthodontics
Mechanical Stress
Observation

Keywords

  • BMP
  • Immunohistochemhistory
  • Mechanical stress
  • Orthodontic force
  • Periodontal ligament

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biomaterials
  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Dentistry(all)

Cite this

Immunohistochemical observation of BMP in the mouse orthodontic periodontal tension sides. / Matsuda, Hirokazu; Muraoka, Rina; Tomoda, Maki; Nakano, Keisuke; Okafuji, Norimasa; Yamada, Kazuhiro; Kawakami, Toshiyuki.

In: Journal of Hard Tissue Biology, Vol. 18, No. 4, 23.03.2010, p. 181-184.

Research output: Contribution to journalArticle

Matsuda, H, Muraoka, R, Tomoda, M, Nakano, K, Okafuji, N, Yamada, K & Kawakami, T 2010, 'Immunohistochemical observation of BMP in the mouse orthodontic periodontal tension sides', Journal of Hard Tissue Biology, vol. 18, no. 4, pp. 181-184. https://doi.org/10.2485/jhtb.18.181
Matsuda, Hirokazu ; Muraoka, Rina ; Tomoda, Maki ; Nakano, Keisuke ; Okafuji, Norimasa ; Yamada, Kazuhiro ; Kawakami, Toshiyuki. / Immunohistochemical observation of BMP in the mouse orthodontic periodontal tension sides. In: Journal of Hard Tissue Biology. 2010 ; Vol. 18, No. 4. pp. 181-184.
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