Immunofluorescence study in purpura pigmentosa chronica

K. Iwatsuki, T. Aoshima, H. Tagami, M. Ohi, M. Yamada

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


Purpura pigmentosa chronica comprises a group of vascular disorders of unknown etiology. In biopsied specimens obtained from 8 patients, the authors observed vascular changes such as fibrinoid degeneration and occlusive damage occasioned by a hyalinized substance as well as swollen endothelia in three. However, in all biopsied specimens, direct immunofluorescence studies demonstrated depositions of C3 or C1q with or without immunoglobulins, and of fibrin in papillary vessels. These findings suggest the possibility that immunological processes are involved in producing the histopathologic features of this disorder.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalActa Dermato-Venereologica
Issue number4
Publication statusPublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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