Abstract
Human adult peripheral blood lymphocytes were successfully immortalized by co-cultivation with irradiated autologous and homologous T-cell lines harbouring human T-cell leukaemia virus-I (HTLV-I). The efficiency of transformation was the same in both cases. The participation of alloantigen stimulation in co-cultivation procedures is discussed, and it is stressed that factors other than alloantigen stimulation might be required for the efficient immortalization of human T-lymphocytes in vitro by HTLV.
Original language | English |
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Pages (from-to) | 82-84 |
Number of pages | 3 |
Journal | Journal of cancer research and clinical oncology |
Volume | 110 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jul 1 1985 |
Externally published | Yes |
Keywords
- Human T-cell leukaemia virus
- Lymphocyte
- Transformation
ASJC Scopus subject areas
- Oncology
- Cancer Research