IgA nephropathy complicated with X-linked thrombocytopenia

Yuki Kakio, Haruhito Adam Uchida, Masashi Kitagawa, Yuka Arata, Ayako Kato, Akiko Inoue-Torii, Norikazu Hinamoto, Ayu Ogawa-Akiyama, Hitoshi Sugiyama, Jun Wada

Research output: Contribution to journalArticle

Abstract

Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.

Original languageEnglish
Pages (from-to)301-307
Number of pages7
JournalActa Medica Okayama
Volume72
Issue number3
Publication statusPublished - Jan 1 2018

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Immunoglobulin A
Wiskott-Aldrich Syndrome
Tonsillectomy
Galactose
Thrombocytopenia 1
Steroids
Kidney
Serum

Keywords

  • Galactose-deficient IgA1
  • IgAN nephropathy
  • Wiskott-Aldrich syndrome
  • X-linked thrombocytopenia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

IgA nephropathy complicated with X-linked thrombocytopenia. / Kakio, Yuki; Uchida, Haruhito Adam; Kitagawa, Masashi; Arata, Yuka; Kato, Ayako; Inoue-Torii, Akiko; Hinamoto, Norikazu; Ogawa-Akiyama, Ayu; Sugiyama, Hitoshi; Wada, Jun.

In: Acta Medica Okayama, Vol. 72, No. 3, 01.01.2018, p. 301-307.

Research output: Contribution to journalArticle

Kakio, Y, Uchida, HA, Kitagawa, M, Arata, Y, Kato, A, Inoue-Torii, A, Hinamoto, N, Ogawa-Akiyama, A, Sugiyama, H & Wada, J 2018, 'IgA nephropathy complicated with X-linked thrombocytopenia', Acta Medica Okayama, vol. 72, no. 3, pp. 301-307.
Kakio Y, Uchida HA, Kitagawa M, Arata Y, Kato A, Inoue-Torii A et al. IgA nephropathy complicated with X-linked thrombocytopenia. Acta Medica Okayama. 2018 Jan 1;72(3):301-307.
Kakio, Yuki ; Uchida, Haruhito Adam ; Kitagawa, Masashi ; Arata, Yuka ; Kato, Ayako ; Inoue-Torii, Akiko ; Hinamoto, Norikazu ; Ogawa-Akiyama, Ayu ; Sugiyama, Hitoshi ; Wada, Jun. / IgA nephropathy complicated with X-linked thrombocytopenia. In: Acta Medica Okayama. 2018 ; Vol. 72, No. 3. pp. 301-307.
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