Abstract
Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.
| Original language | English |
|---|---|
| Pages (from-to) | 301-307 |
| Number of pages | 7 |
| Journal | Acta Medica Okayama |
| Volume | 72 |
| Issue number | 3 |
| Publication status | Published - Jan 1 2018 |
Fingerprint
Keywords
- Galactose-deficient IgA1
- IgAN nephropathy
- Wiskott-Aldrich syndrome
- X-linked thrombocytopenia
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
IgA nephropathy complicated with X-linked thrombocytopenia. / Kakio, Yuki; Uchida, Haruhito Adam; Kitagawa, Masashi; Arata, Yuka; Kato, Ayako; Inoue-Torii, Akiko; Hinamoto, Norikazu; Ogawa-Akiyama, Ayu; Sugiyama, Hitoshi; Wada, Jun.
In: Acta Medica Okayama, Vol. 72, No. 3, 01.01.2018, p. 301-307.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - IgA nephropathy complicated with X-linked thrombocytopenia
AU - Kakio, Yuki
AU - Uchida, Haruhito Adam
AU - Kitagawa, Masashi
AU - Arata, Yuka
AU - Kato, Ayako
AU - Inoue-Torii, Akiko
AU - Hinamoto, Norikazu
AU - Ogawa-Akiyama, Ayu
AU - Sugiyama, Hitoshi
AU - Wada, Jun
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.
AB - Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.
KW - Galactose-deficient IgA1
KW - IgAN nephropathy
KW - Wiskott-Aldrich syndrome
KW - X-linked thrombocytopenia
UR - http://www.scopus.com/inward/record.url?scp=85048869662&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85048869662&partnerID=8YFLogxK
M3 - Article
C2 - 29926009
AN - SCOPUS:85048869662
VL - 72
SP - 301
EP - 307
JO - Acta Medica Okayama
JF - Acta Medica Okayama
SN - 0386-300X
IS - 3
ER -