Abstract
Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission.
Original language | English |
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Pages (from-to) | 301-307 |
Number of pages | 7 |
Journal | Acta medica Okayama |
Volume | 72 |
Issue number | 3 |
Publication status | Published - 2018 |
Keywords
- Galactose-deficient IgA1
- IgAN nephropathy
- Wiskott-Aldrich syndrome
- X-linked thrombocytopenia
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)