Two isoforms of calcineurin β subunit(β1 and β2) were identified in rat testis by a monoclonal antibody Val. Both β1 and β2 were recovered in calmodulin binding protein fraction and showed calcium shift on SDS-polyacrylamide gel electrophoresis which is the specific character for EF-hand calcium binding protein. β2 showed same apparent molecular weight on SDS-PAGE as that of brain calcineurin and was found in wide variety of tissues. β1 was shown to have six amino acid polypepeptide sequence and it showed higher molecular weight than brain β and was specific for testis.
|Number of pages||5|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - Jan 15 1992|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology