Identification of Pheophorbide a and Its Related Compounds as Possible Anti-tumor Promoters in the Leaves of Neptunia oleracea

Yoshimasa Nakamura, Akira Murakami, Koichi Koshimizu, Hajime Ohigashi

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Six chlorophyll-related compounds isolated from leaves of Neptunia oleracea (Leguminosae) inhibited the activation of tumor promoter-induced Epstein-Barr virus (EBV). Photo-irradiation of pheophorbide a, the major active constituent, did not enhance this inhibitory activity, and thus ruled out any photosensitizing effect playing the major role.

Original languageEnglish
Pages (from-to)1028-1030
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume60
Issue number6
DOIs
Publication statusPublished - Jan 1996
Externally publishedYes

Keywords

  • Anti-tumor promoter
  • Chlorophylls
  • Epstein-Barr virus
  • Pheophorbides
  • Photocytotoxicity

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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