Identification of pheophorbide a and its related compounds as possible anti-tumor promoters in the leaves of Neptunia oleracea

Yoshimasa Nakamura, Akira Murakami, Koichi Koshimizu, Hajime Ohigashi

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Six chlorophyll-related compounds isolated from leaves of Neptunia oleracea (Leguminosae) inhibited the activation of tumor promoter- induced Epstein-Barr virus (EBV). Photo-irradiation of pheophorbide a, the major active constituent, did not enhance this inhibitory activity, and thus ruled out any photosensitizing effect playing the major role.

Original languageEnglish
Pages (from-to)1028-1030
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume60
Issue number6
Publication statusPublished - Jun 1996
Externally publishedYes

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Keywords

  • anti-tumor promoter
  • chlorophylls
  • Epstein Barr virus
  • pheophorbides
  • photocytotoxicity

ASJC Scopus subject areas

  • Food Science
  • Applied Microbiology and Biotechnology
  • Chemistry (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biotechnology

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