Abstract
BACKGROUND: Syncope in patients with Brugada syndrome is usually associated with ventricular tachyarrhythmia, but some episodes of syncope can be related to autonomic disorders. OBJECTIVE: The purpose of this study was to investigate the characteristics of syncope to differentiate high-risk syncope episodes from low-risk events in patients with Brugada syndrome. METHODS: We studied 84 patients with type 1 electrocardiogram and syncope. Patients were divided into 2 groups: patients with prodrome (prodromal group; n = 41) and patients without prodrome (nonprodromal group; n = 43). RESULTS: Ventricular fibrillation (VF) was documented at index event in 19 patients: 4 patients (21%) with documented VF experienced a prodrome prior to the onset of VF, whereas 15 patients (79%) did not have symptoms prior to documented VF (P
| Original language | English |
|---|---|
| Pages (from-to) | 752-759 |
| Number of pages | 8 |
| Journal | Heart Rhythm |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2012 |
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Keywords
- Brugada syndrome
- Neurally mediated syncope
- Prodrome
- Syncope
- Ventricular fibrillation
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology (medical)
Cite this
Identification of high-risk syncope related to ventricular fibrillation in patients with Brugada syndrome. / Take, Yutaka; Morita, Hiroshi; Toh, Norihisa; Nishii, Nobuhiro; Nagase, Satoshi; Nakamura, Kazufumi; Kusano, Kengo F.; Ohe, Tohru; Itoh, Hiroshi.
In: Heart Rhythm, Vol. 9, No. 5, 05.2012, p. 752-759.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Identification of high-risk syncope related to ventricular fibrillation in patients with Brugada syndrome
AU - Take, Yutaka
AU - Morita, Hiroshi
AU - Toh, Norihisa
AU - Nishii, Nobuhiro
AU - Nagase, Satoshi
AU - Nakamura, Kazufumi
AU - Kusano, Kengo F.
AU - Ohe, Tohru
AU - Itoh, Hiroshi
PY - 2012/5
Y1 - 2012/5
N2 - BACKGROUND: Syncope in patients with Brugada syndrome is usually associated with ventricular tachyarrhythmia, but some episodes of syncope can be related to autonomic disorders. OBJECTIVE: The purpose of this study was to investigate the characteristics of syncope to differentiate high-risk syncope episodes from low-risk events in patients with Brugada syndrome. METHODS: We studied 84 patients with type 1 electrocardiogram and syncope. Patients were divided into 2 groups: patients with prodrome (prodromal group; n = 41) and patients without prodrome (nonprodromal group; n = 43). RESULTS: Ventricular fibrillation (VF) was documented at index event in 19 patients: 4 patients (21%) with documented VF experienced a prodrome prior to the onset of VF, whereas 15 patients (79%) did not have symptoms prior to documented VF (P
AB - BACKGROUND: Syncope in patients with Brugada syndrome is usually associated with ventricular tachyarrhythmia, but some episodes of syncope can be related to autonomic disorders. OBJECTIVE: The purpose of this study was to investigate the characteristics of syncope to differentiate high-risk syncope episodes from low-risk events in patients with Brugada syndrome. METHODS: We studied 84 patients with type 1 electrocardiogram and syncope. Patients were divided into 2 groups: patients with prodrome (prodromal group; n = 41) and patients without prodrome (nonprodromal group; n = 43). RESULTS: Ventricular fibrillation (VF) was documented at index event in 19 patients: 4 patients (21%) with documented VF experienced a prodrome prior to the onset of VF, whereas 15 patients (79%) did not have symptoms prior to documented VF (P
KW - Brugada syndrome
KW - Neurally mediated syncope
KW - Prodrome
KW - Syncope
KW - Ventricular fibrillation
UR - http://www.scopus.com/inward/record.url?scp=84859963099&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859963099&partnerID=8YFLogxK
U2 - 10.1016/j.hrthm.2011.11.045
DO - 10.1016/j.hrthm.2011.11.045
M3 - Article
VL - 9
SP - 752
EP - 759
JO - Heart Rhythm
JF - Heart Rhythm
SN - 1547-5271
IS - 5
ER -