Abstract
To clarify the molecular basis underlying the neural function of the honeybee mushroom bodies (MBs), we identified three genes preferentially expressed in MB using cDNA microarrays containing 480 differential display-positive candidate cDNAs expressed locally or differentially, dependent on caste/aggressive behavior in the honeybee brain. One of the cDNAs encodes a putative type I inositol 1,4,5-trisphosphate (IP3) 5-phosphatase and was expressed preferentially in one of two types of intrinsic MB neurons, the large-type Kenyon cells, suggesting that IP3-mediated Ca2+ signaling is enhanced in these neurons.
Original language | English |
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Pages (from-to) | 230-234 |
Number of pages | 5 |
Journal | FEBS Letters |
Volume | 513 |
Issue number | 2-3 |
DOIs | |
Publication status | Published - Feb 27 2002 |
Externally published | Yes |
Keywords
- Brain
- Differential display
- Honeybee
- Inositol 1,4,5-trisphosphate 5-phosphatase
- Mushroom body
- cDNA microarray
ASJC Scopus subject areas
- Biophysics
- Structural Biology
- Biochemistry
- Molecular Biology
- Genetics
- Cell Biology